Imaging device based on multi-photon depth imaging and imaging probe thereof
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Solution Overview
Problem
Existing multi-photon imaging technologies are limited by the complexity of their optical paths, requiring large-scale devices and are unable to efficiently transmit excitation light of multiple wavelengths simultaneously, leading to suboptimal imaging quality and synchronization issues.
Innovation Solution
A miniaturized imaging device with a separated probe and main unit design, utilizing an input optical fiber with a target bandwidth to carry combined laser beams of different wavelengths, and a coupling module to transmit excitation light directly to the probe, enabling simultaneous multi-photon effects at various wavelengths.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If a large-scale device is used to implement multi-photon imaging, then the imaging quality can be maintained, but the device complexity and size increase significantly
Solution Approach 1:
The imaging system is divided into two independent parts: a compact imaging probe for actual imaging and a separate main unit housing the laser devices and optical detectors. This segmentation allows the probe to be miniaturized while the main unit can contain the complex components, resolving the contradiction between imaging quality and device complexity.
Solution Approach 2:
An optical fiber is introduced as an intermediary to transmit the combined laser beam from the main unit to the imaging probe. This allows the complex laser generation and beam combining components to be separated from the probe, enabling probe miniaturization while maintaining full imaging functionality and quality.
2Productivity
If multiple laser beams of different wavelengths are transmitted through a single optical fiber, then the imaging efficiency improves, but the energy transmission loss increases
Solution Approach 1:
Multiple laser beams of different wavelengths are combined into a single combined laser beam using a coupling module before transmission through the optical fiber. This merging approach improves imaging efficiency by enabling simultaneous multi-wavelength excitation while the patent specifically selects an optical fiber with appropriate bandwidth to minimize energy transmission loss.
Solution Approach 2:
The patent specifies that the optical fiber should have a target bandwidth that meets multi-photon imaging requirements, optimizing the fiber's transmission parameters to reduce energy loss across the multiple wavelengths being transmitted. This parameter optimization resolves the contradiction between efficient multi-wavelength transmission and energy conservation.
3Volume of moving object
If the optical path is simplified for miniaturization, then the device size reduces, but the ability to transmit multiple wavelengths simultaneously deteriorates
Solution Approach 1:
The system is segmented into a compact probe and a separate main unit. The probe contains only the essential imaging components (imaging apparatus, focusing position control), achieving miniaturization, while the main unit houses the laser devices and coupling module needed for multi-wavelength transmission, preserving full functionality.
Solution Approach 2:
The optical fiber acts as an intermediary that bridges the simplified probe and the full-featured main unit. This allows the probe to be miniaturized without compromising multi-wavelength transmission capability, as this functionality is provided by the external main unit through the fiber connection.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The solution allows for high-quality, synchronized multi-photon imaging of multiple substances by simultaneously exciting different internal structures, improving integration and imaging efficiency while maintaining excitation power and reducing energy loss.
Implementation Method 1
a coupling module, the laser devices are configured to provide laser beams meeting an imaging requirement, the coupling module is configured to couple laser beams released by the at least two laser devices into a combined laser beam
Implementation Method 2
An end of the input optical fiber is connected to the coupling module and the other end is connected to the imaging probe for transmitting the combined laser beam to the imaging probe
Implementation Method 3
the imaging apparatus that is based on multi-photon depth imaging and configured to: convert the combined laser beam into excitation light; focus the excitation light at an internal focusing position of an imaging object to trigger a multi-photon effect
Implementation Method 4
collect optical signals generated by the multi-photon effect
Implementation Method 5
The beam splitting module is configured to split the optical signals into at least two optical signal splitting beams
Data Source
AI summary
Disclosed are an imaging device based on multi-photon depth imaging and an imaging probe thereof, and a miniaturized imaging probe is implemented by using a separated structure. During imaging, the imaging probe may be fixedly connected to an imaging object, and an optical signal inside the imaging object may be collected by exciting a multi-photon effect inside the imaging object by excitation light to detect an internal status in the imaging object.