Multiscale Lens Systems for Parallel Well Plate Imaging

The patent divides the well plate into multiple regions and uses multiple detectors to simultaneously image different wells or regions. Each detector is assigned to specific wells, allowing parallel processing of multiple samples at the same time, thus reducing total processing time while maintaining individual well imaging quality

The patent transitions from sequential imaging (one well at a time) to parallel imaging by adding a spatial dimension with multiple detectors positioned at different locations. This allows simultaneous capture of multiple wells in a single operation, converting a 1D sequential process into a 2D parallel process

Instead of using a single moving scanner, the patent segments the imaging function into multiple stationary detectors, each responsible for specific wells. This eliminates the need for moving parts while maintaining the ability to image all wells, thereby improving productivity without increasing device complexity

The patent replaces the mechanical scanning system with a stationary multi-detector optical system. Instead of moving a single detector across wells, multiple detectors are positioned simultaneously to capture multiple wells at once, substituting mechanical motion with parallel optical detection

The patent assigns different wavelength ranges to different light sources and detectors, creating local spectral differentiation. Each light source operates at a specific wavelength band with dedicated detectors, allowing multiple sources to be positioned close together without optical interference since each detector is tuned to its assigned wavelength range

The patent changes the wavelength parameter of the light sources to differentiate their signals. By using light sources at different wavelengths (e.g., blue, green, red LEDs) and matching detectors to these wavelengths, the system can multiplex multiple imaging operations simultaneously without signal interference, enabling high throughput