Multi-spectral fundus imaging with dynamic visual stimulation
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Solution Overview
Problem
Traditional multi-spectral fundus imaging primarily focuses on static structural imaging, which is not suitable for early screening and diagnosis of fundus diseases as it fails to detect significant physiological structural changes in early patients.
Innovation Solution
A multi-spectral fundus imaging system that incorporates dynamic visual stimulation, allowing for the capture of physiological changes in the fundus before and after optical stimulation, thereby enabling dynamic multi-spectral fundus functional imaging.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If traditional multi-spectral fundus imaging is used for static structural imaging, then the imaging system is simple and easy to operate, but it cannot detect significant physiological structural changes in early patients
Solution Approach 1:
The patent transforms the static imaging system into a dynamic one by introducing visual stimulation that induces physiological changes in the fundus. The system captures images before and after stimulation to detect dynamic functional changes, enabling early disease detection through physiological response monitoring rather than relying solely on static structural changes.
Solution Approach 2:
The patent employs periodic visual stimulation (such as alternating light and dark periods) to elicit rhythmic physiological responses in the fundus. This periodic action allows the system to capture multiple phases of the physiological response, enhancing the ability to detect subtle early-stage pathological changes that would be invisible in static images.
2Reliability
If dynamic visual stimulation is added to enable functional imaging, then early diagnosis accuracy is improved, but the device complexity increases
Solution Approach 1:
The patent designs the imaging system to perform multiple functions: static structural imaging, dynamic functional imaging, and physiological response monitoring. By integrating these functions into a single system, the patent achieves high diagnostic reliability for early disease detection without requiring separate specialized devices, thus managing complexity through multi-functionality.
Solution Approach 2:
The system incorporates feedback mechanisms where the physiological responses to visual stimulation are monitored and used to adjust subsequent imaging parameters. This feedback loop enhances diagnostic reliability by adapting to individual patient responses while maintaining systematic control over the increased device complexity.
3Measurement precision
If multiple wavelengths are used for multi-spectral imaging, then the spectral range is widened for better tissue differentiation, but the acquisition time increases
Solution Approach 1:
The patent performs preliminary actions by capturing a baseline static multi-spectral image before visual stimulation. This preliminary capture establishes reference data for all wavelengths simultaneously, allowing subsequent dynamic changes to be detected by comparing against this pre-acquired reference, thus reducing the time penalty of multi-wavelength imaging.
Solution Approach 2:
The system maintains continuous useful action by overlapping the acquisition of multi-spectral images during the visual stimulation process. Rather than sequentially capturing each wavelength, the system continuously acquires multi-spectral data throughout the stimulation period, ensuring that dynamic physiological changes are captured across all wavelengths without temporal gaps.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This approach enhances the accuracy of early diagnosis and screening of fundus diseases by providing functional imaging that can detect dynamic responses and changes in the fundus, improving the universality and reliability of diagnostic methods.
Implementation Method 1
the monochromatic excitation light emitted by the multi-spectral light source is reflected into the fundus through the central hole of the mid-pass mirror; the reflected imaging light passes through the central hole of the mid-pass mirror and the imaging focusing lens group in sequence
Implementation Method 2
a pattern sent by the optical stimulation device is transmitted to the fundus through the image focusing lens group and the central hole of the mid-pass mirror in sequence
Data Source
AI summary
The present application discloses a multi-spectral fundus imaging system and method using dynamic visual stimulation, where the imaging system includes: a multi-spectral light source capable of emitting multiple different wavelengths; a mid-pass mirror being a reflecting mirror with a central hole penetrating the reflecting mirror; an imaging focusing lens group; an image acquisition device; and a controller configured to control the multi-spectral light source and the image acquisition device to work synchronously; a pattern sent by the optical stimulation device is transmitted to the fundus through the image focusing lens group and the central hole of the mid-pass mirror in sequence; an imaging light reflected from the fundus passes through the central hole of the mid-pass mirror and the imaging focusing lens group in sequence; the image acquisition device acquires the image to complete a multi-spectral fundus image acquisition.