Multispectral Illumination System for Retinal Surgery

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Solution Overview

Problem

Current medical light sources for retinal surgery pose a risk of iatrogenic phototoxicity due to excessive ultraviolet and blue light exposure, which can cause retinal damage, and existing filters that block harmful wavelengths compromise color rendition and are not entirely effective.

Innovation Solution

An observation system that uses a multispectral programmable light source with adaptive illumination techniques, such as camera shutter synchronization, multiplexed spectrum imaging, color companding, and adaptive multispectral imaging to reduce exposure to harmful wavelengths while maintaining image quality by interleaving white light with less damaging light sources like red or infrared, and compensating images to appear as if they were taken under continuous white light.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Illumination intensity

If conventional white light sources are used for retinal illumination, then adequate illumination of retinal structures is achieved, but phototoxicity risk increases due to excessive ultraviolet and blue light exposure

Engineering Contradiction:
Improveillumination of retinal structuresVSAvoidphototoxicity risk
Core Design Contradiction:
Illumination intensityVSObject-affected harmful factors

Solution Approach 1:

The illumination spectrum is segmented into multiple discrete wavelength bands (e.g., 450-480nm blue, 480-530nm cyan, 530-560nm green, 560-590nm yellow-green, 590-650nm red) using individual LEDs. This allows selective activation of only the necessary spectral components for retinal imaging while excluding harmful UV and excessive blue wavelengths, thereby maintaining adequate illumination without phototoxicity

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system dynamically changes illumination parameters by adjusting the intensity and spectral composition of individual LED wavelengths based on the specific surgical task and tissue type. This enables optimization of illumination quality while minimizing harmful exposure by suppressing certain wavelength bands during procedures

Inventive Principle:
Principle #35Parameter changes

2Object-affected harmful factors

If filters are used to block harmful wavelengths, then phototoxicity is reduced, but color rendition is compromised and effectiveness is limited

Engineering Contradiction:
Improvephototoxicity reductionVSAvoidcolor rendition
Core Design Contradiction:
Object-affected harmful factorsVSLoss of information

Solution Approach 1:

Instead of using filters to remove harmful wavelengths from white light, the system extracts only the necessary safe wavelengths by using individual LEDs that emit specifically in the 450-650nm range. This selective emission approach inherently excludes UV and excessive blue light while preserving all necessary visible spectrum components for accurate color rendition without requiring post-illumination filtering

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The illumination system uses a composite approach by combining multiple LED sources with different spectral characteristics to create a tailored illumination spectrum. This composite light source provides both phototoxicity protection and full color rendering capability simultaneously, overcoming the limitations of single-source illumination with filters

Inventive Principle:
Principle #40Composite materials

3Object-affected harmful factors

If multispectral illumination with intermittent white light is used, then phototoxicity is reduced, but image quality may be compromised without compensation

Engineering Contradiction:
Improvephototoxicity minimizationVSAvoidimage quality
Core Design Contradiction:
Object-affected harmful factorsVSLoss of information

Solution Approach 1:

The system uses periodic intermittent illumination with white light bursts synchronized to the camera frame rate, alternating with periods of reduced-intensity or filtered illumination. This periodic action allows accumulation of sufficient light signal during white light bursts while minimizing total phototoxic exposure during the procedure through the darker intervals

Inventive Principle:
Principle #19Periodic action

Solution Approach 2:

The system incorporates real-time feedback through the imaging system to monitor tissue appearance and illumination adequacy. This feedback allows dynamic adjustment of illumination intensity and spectral composition to maintain optimal image quality while minimizing phototoxicity, ensuring that compensation is sufficient without over-illuminating

Inventive Principle:
Principle #23Feedback

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Significantly reduces phototoxicity risk during retinal surgery by minimizing exposure to harmful wavelengths while preserving color information and image quality, allowing for safer and more effective surgical procedures.

Implementation Method 1

an illumination system comprising a plurality of light-emitting diodes (LEDs) arranged in an array, with each LED emitTABLE at a different wavelength

Methodology Applied
Scientific EffectLight emission from LEDs: Light Emitting Diode

Implementation Method 2

an imaging system configured to image at least a portion of the light-sensitive tissue upon being illuminated by the illumination system

Methodology Applied
Scientific EffectLight detection and imaging: Photography

Data Source

PatentUS10188281B2Programmable multispectral illumination system for surgery and visualization of light-sensitive tissues
Publication Date: 2019.01.29 JOHNS HOPKINS UNIVERSITY
  • US10188281B2 patent drawing
  • US10188281B2 patent drawing
  • US10188281B2 patent drawing

AI summary

An observation system for viewing light-sensitive tissue includes an illumination system configured to illuminate the light-sensitive tissue, an imaging system configured to image at least a portion of the light-sensitive tissue upon being illuminated by the illumination system, and an image display system in communication with the imaging system to display an image of the portion of the light-sensitive tissue. The illumination system is configured to illuminate the light-sensitive tissue with a reduced amount of light within a preselected wavelength range compared to multispectral illumination light, and the image of the portion of the light-sensitive tissue is compensated for the reduced amount of light within the preselected frequency range to approximate an image of the light-sensitive tissue under the multispectral illumination.