Multispectral Wound And Burn Imaging for AI-ML Healing Prediction

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Solution Overview

Problem

Current wound and burn assessments rely heavily on visual clinical judgment, which is inaccurate, and existing AI/ML models fail to adequately consider tissue blood flow and oxygen information, limiting their effectiveness in wound healing prediction.

Innovation Solution

A multispectral imaging system using multiple wavelength bands and synchronized imaging channels, combined with AI-ML analysis, to provide detailed tissue physiology information and enhance wound assessment accuracy.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If visual clinical judgment is used for wound assessment, then the method is simple and quick, but the accuracy is low (only 70% for trained specialists, 50% for front line physicians)

Engineering Contradiction:
Improvewound assessment accuracyVSAvoidimaging system complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The imaging system divides the wound assessment into multiple spectral bands (visible light, ultraviolet, near infrared) and multiple imaging channels (anatomical structure, functional characteristics, compositional characteristics). Each band and channel provides specific information about different tissue properties, allowing comprehensive assessment beyond single-modality limitations.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system transitions from two-dimensional visible color images to multi-dimensional spectral data by adding ultraviolet and near infrared bands. This dimensional expansion enables detection of tissue properties (blood flow, oxygenation, moisture) that are invisible to the human eye but critical for accurate wound assessment.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Measurement precision

If existing AI/ML models are used for wound healing prediction, then processing is automated, but they fail to consider tissue blood flow and oxygen information

Engineering Contradiction:
Improvewound healing prediction accuracyVSAvoidtissue physiology information
Core Design Contradiction:
Measurement precisionVSLoss of information

Solution Approach 1:

The imaging system is designed to simultaneously capture multiple types of tissue information across different spectral bands and imaging channels. The same multispectral imaging platform provides anatomical structure visualization, functional characteristics (blood flow, oxygenation), and compositional characteristics (moisture, pH) in a single integrated system, ensuring no critical information is lost.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The system introduces an intermediary multispectral imaging layer between the wound tissue and the AI/ML analysis. This imaging layer captures and processes physical optical signals into multiple data channels, which then serve as enriched input features for the machine learning models, enabling them to detect tissue physiology information that would otherwise be inaccessible.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Loss of information

If multispectral imaging with multiple wavelength bands is used, then tissue physiology information is captured, but the device complexity and hardware requirements increase

Engineering Contradiction:
Improvetissue physiology informationVSAvoidimaging hardware complexity
Core Design Contradiction:
Loss of informationVSDevice complexity

Solution Approach 1:

The system merges multiple imaging modalities (visible light imaging, ultraviolet imaging, near infrared imaging) into a single integrated multispectral imaging platform. By combining these modalities spatially and temporally synchronized, the system captures comprehensive tissue information while sharing common hardware components (light sources, detectors, processing units) to manage complexity.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The imaging system performs continuous multispectral capture across multiple wavelength bands in a synchronized manner, maintaining continuous acquisition of anatomical, functional, and compositional information. This continuous multi-band imaging ensures complete data collection without requiring separate sequential measurements, improving efficiency despite the complexity of multiple sensors.

Inventive Principle:
Principle #20Continuity of useful action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Improves wound assessment accuracy by integrating multispectral imaging and AI-ML, enabling precise tissue analysis and predictive wound healing insights.

Implementation Method 1

Multispectral technologies allow combining light of visible light, ultraviolet (UV) and near infrared (NIR) wavelengths during the imaging process and provide benefits of visualizing anatomical structure and quantitively visualizing distribution of functional, physiologic and compositional characteristics of organs and tissues

Methodology Applied
Scientific EffectMultispectral imaging:

Implementation Method 2

The imaging hardware can include a light source of multiple bands of wavelength of noncoherent and coherent light for broadband, narrowband, fluorescence, autofluorescence, Laser Speckle Imaging (LSI), Laser Doppler Imaging (LDI)

Methodology Applied
Scientific EffectLaser speckle imaging:

Implementation Method 3

Laser Doppler Imaging (LDI), tissue oxygenation imaging

Methodology Applied
Scientific EffectDoppler effect: Doppler Effect

Implementation Method 4

The imaging hardware can include a light source of multiple bands of wavelength of noncoherent and coherent light for broadband, narrowband, fluorescence, autofluorescence

Methodology Applied
Scientific EffectFluorescence: Fluorescence

Implementation Method 5

capturing multiple channels of images in a temporally and spatially synchronized fashion for image processing, analysis, visualization, and reporting

Methodology Applied
Scientific EffectTemporal and spatial synchronization:

Data Source

PatentUS20250216261A1Methods of multispectral imaging and predictive analysis of wounds and burns based on machine learning and related systems
Publication Date: 2025.07.03 EAST CAROLINA UNIVERSITY
  • US20250216261A1 patent drawing
  • US20250216261A1 patent drawing
  • US20250216261A1 patent drawing

AI summary

Methodology of various imaging modalities and engineering features are provided for multispectral soft tissue imaging architecture. The architectural designs comprise hardware of multiple ranges of wavelength for illumination and camera sensing and software for image acquisition, processing, feature abstraction, artificial intelligence-machine learning (AI-ML) analysis, visualization, and reporting. Embodiments of imaging hardware in a medical device can include a light source of multiple bands of wavelength of noncoherent and coherent light for broadband, narrowband, fluorescence, autofluorescence, Laser Speckle Imaging (LSI), Laser Doppler Imaging (LDI), tissue oxygenation imaging, and other variation of soft tissue imaging modalities. The imaging software can include temporally and spatially synchronized acquisition of multiple imaging channels, image processing based on physics principle and mathematical equations of each imaging modality, feature engineering to abstract key parameters, AI-ML training and predictive analysis, image fusion-based visualization and report. The system is designed to be either an addon to smart phones, tablets or independent handheld equipment based on embedded System On Module (SOM).