Multispectrum Endoscope Fiber Layout for Multi-Wavelength Fluorescence

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Solution Overview

Problem

Conventional endoscopes using a single wavelength laser light source face challenges in simultaneously observing multiple fluorescent images, suffer from speckle noise and multi-modal noise, and are limited in adjusting the field of view, leading to degraded image quality and increased costs and time for additional photographing.

Innovation Solution

A multi-spectrum endoscope system with a first light source emitting infrared rays of multiple wavelengths, multi-mode optical fibers, a second light source for visible light, and a light detection device with a wavelength separator to distinguish and detect fluorescent signals of different wavelengths, while reducing speckle and multi-modal noise.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Device complexity

If a single wavelength laser light source is used, then the device complexity is reduced, but the ability to simultaneously observe multiple fluorescent images with different wavelengths is lost

Engineering Contradiction:
Improvelight source configurationVSAvoidmulti-wavelength fluorescent observation capability
Core Design Contradiction:
Device complexityVSAdaptability or versatility

Solution Approach 1:

The patent combines multiple laser light sources with different wavelengths into a single integrated endoscope system. The light source unit includes multiple laser sources (e.g., 405nm, 488nm, 561nm, 640nm) that can be selectively activated to excite different fluorescent markers, enabling multi-spectrum observation without requiring separate endoscope devices.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The endoscope system is designed with universal functionality to support multiple wavelengths of laser excitation and detect corresponding fluorescent signals. The light source unit can selectively emit different wavelengths, and the detection unit can capture fluorescent signals across multiple spectra, making the system adaptable to various fluorescent imaging applications.

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Illumination intensity

If a laser light source is used, then the brightness and intensity of exciting light is improved, but speckle noise and multi-modal noise occur degrading image quality

Engineering Contradiction:
Improvelaser exciting light intensityVSAvoidspeckle noise and multi-modal noise
Core Design Contradiction:
Illumination intensityVSObject-affected harmful factors

Solution Approach 1:

The patent acknowledges the presence of speckle noise and multi-modal noise as inherent characteristics of laser light but converts this potential harm into a benefit by using the high intensity and coherence of laser light for effective fluorescence excitation. The system manages the noise through careful optical design and signal processing while maintaining the advantageous high brightness of laser illumination.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

3Adaptability or versatility

If multiple light sources are used to enable multi-wavelength excitation, then the fluorescent imaging capability is improved, but the total thickness of the endoscope increases causing patient discomfort

Engineering Contradiction:
Improvemulti-wavelength fluorescent imaging capabilityVSAvoidendoscope thickness
Core Design Contradiction:
Adaptability or versatilityVSLength of moving object

Solution Approach 1:

The patent employs a nested structure where multiple optical components are arranged concentrically within the endoscope shaft. The light source unit, optical fibers, and detection components are integrated in a compact, layered configuration that minimizes the overall diameter while accommodating multiple wavelengths of laser excitation and corresponding detection pathways.

Inventive Principle:
Principle #7Nested doll (Nesting)

Solution Approach 2:

The patent transitions from a planar arrangement of components to a three-dimensional integrated structure. Multiple optical fibers and light sources are arranged in different spatial dimensions and orientations, allowing efficient use of the endoscope cross-sectional area and reducing the overall thickness while maintaining multi-wavelength capability.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

4Device complexity

If a single light source is used, then the device structure is simplified, but the ability to adjust the field of view area is limited

Engineering Contradiction:
Improvelight source and optical systemVSAvoidfield of view adjustability
Core Design Contradiction:
Device complexityVSArea of moving object

Solution Approach 1:

The patent incorporates dynamic control capabilities that allow the system to adjust operational parameters in real-time. The light source unit can selectively activate different wavelengths, and the detection system can dynamically adjust sensitivity and integration time, enabling flexible field of view adjustment and optimization for different imaging conditions without physical reconfiguration.

Inventive Principle:
Principle #15Dynamics

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables simultaneous output and detection of visible light and fluorescent signals with different wavelengths, reducing noise and enhancing image quality, allowing for precise identification and treatment of specific cells.

Implementation Method 1

a first light source for emitting an infrared ray having a plurality of wavelengths

Methodology Applied
Scientific EffectLight emission: Light

Implementation Method 2

a plurality of multi-mode optical fibers for providing the infrared ray which is emitted from the first light source with guidance toward a sample or a cell

Methodology Applied
Scientific EffectOptical fiber transmission: Optical Fibre

Implementation Method 3

a lens part for receiving a fluorescent signal which is emitted from the sample

Methodology Applied
Scientific EffectLight refraction and focusing: Lens

Implementation Method 4

a multi-spectrum light detection device... with a wavelength separator to distinguish and detect fluorescent signals of different wavelengths

Methodology Applied
Scientific EffectWavelength separation: Dispersion (of waves)

Implementation Method 5

detect fluorescent signals that emit different wavelengths by radiating pieces of laser light having a plurality of wavelengths

Methodology Applied
Scientific EffectFluorescence: Fluorescence

Data Source

PatentUS20250366705A1Multispectrum endoscope and endoscope system comprising same
Publication Date: 2025.12.04 METAPLEBIO CO LTD
  • US20250366705A1 patent drawing
  • US20250366705A1 patent drawing
  • US20250366705A1 patent drawing

AI summary

The present invention relates to a multispectrum endoscope and an endoscope system comprising same. The multispectrum endoscope of the present invention comprises: a first light source emitting infrared rays having a plurality of wavelengths; a plurality of multimode optical fibers for guiding the infrared rays emitted from the first light source toward a sample; a second light source emitting a visible ray; an optical fiber for guiding the visible ray emitted from the second light source toward the sample; a lens part for receiving a fluorescent signal emitted from the sample and a visible light signal reflected off the sample; and an optical fiber bundle for guiding the fluorescent signal and/or the visible light signal received by the lens part toward a multispectrum photodetector, wherein the optical fiber bundle is disposed so as to be surrounded by the plurality of multimode optical fibers, and the end portion of the multispectrum endoscope emitting the visible ray surrounds at least a portion of the plurality of multimode optical fibers.