Muscle Relaxation Monitoring Calibration via Adaptive Current Steps

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Solution Overview

Problem

Existing muscle relaxation monitoring systems face challenges in detecting supramaximal stimulation current values efficiently, particularly in infants and neonates, leading to prolonged calibration times and increased physical burden due to the need for high initial stimulation current values.

Innovation Solution

A muscle relaxation monitoring apparatus that sets an initial stimulation current value lower than the maximum, using variable processes to increment or decrement the current value by a step value at predetermined timings, allowing for the detection of supramaximal stimulation through amplitude peak value comparisons, thereby reducing the burden and time required for calibration.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If the calibration process starts at the maximal stimulation current value (e.g., 60 mA), then the supramaximal stimulation can be detected, but the calibration time becomes excessively long and the physical burden on the subject increases

Engineering Contradiction:
Improvedetection of supramaximal stimulationVSAvoidcalibration time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent applies preliminary action by setting an initial stimulation current value that is already close to the expected supramaximal value (e.g., 40-50 mA) rather than starting from the maximum value (60 mA). This preliminary positioning reduces the number of iterative steps needed to find the supramaximal stimulation, thereby shortening calibration time while maintaining detection accuracy.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent implements dynamics by making the stimulation current value adaptive and variable during the calibration process. The system dynamically adjusts the current value based on real-time muscle response feedback, increasing or decreasing the current in steps until the supramaximal stimulation is identified. This dynamic adjustment allows the system to efficiently converge on the target value without following a fixed, time-consuming sequence.

Inventive Principle:
Principle #15Dynamics

2Measurement precision

If the calibration process starts at the maximal stimulation current value (e.g., 60 mA), then the supramaximal stimulation can be detected, but the physical burden and potential damage to the subject increases

Engineering Contradiction:
Improvedetection of supramaximal stimulationVSAvoidphysical burden on subject
Core Design Contradiction:
Measurement precisionVSObject-affected harmful factors

Solution Approach 1:

The patent applies preliminary action by pre-setting the initial stimulation current to a value closer to the expected supramaximal range (40-50 mA) rather than starting at the maximum value. This preliminary configuration reduces the need to apply excessively high currents during calibration, thereby minimizing physical burden and potential damage to the subject while still enabling accurate detection.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent applies the skipping principle by rapidly progressing through current values in controlled steps from the initial value toward the supramaximal range. Instead of methodically testing every possible current level from maximum, the system efficiently skips through intermediate values, quickly identifying the supramaximal stimulation point with minimal exposure to high current levels that could cause harm.

Inventive Principle:
Principle #21Skipping (Rushing through)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables the detection of supramaximal stimulation current values in a shorter time frame while minimizing physical burden on subjects, particularly infants and neonates, by starting with lower initial stimulation current values and adjusting accordingly.

Implementation Method 1

an electrical stimulation of a predetermined current value is applied to a peripheral nerve leading to a portion (muscle) to be observed

Methodology Applied
Scientific EffectElectrical stimulation: Electrical Impedance Tomography

Implementation Method 2

detects an action potential of the muscle as an electric signal

Methodology Applied
Scientific EffectAction potential detection: Electrical Impedance Tomography

Data Source

PatentUS20220401007A1Muscle relaxation monitoring apparatus and calibration processing method
Publication Date: 2022.12.22 NIHON KOHDEN CORP
  • US20220401007A1 patent drawing
  • US20220401007A1 patent drawing
  • US20220401007A1 patent drawing

AI summary

A muscle relaxation monitoring apparatus includes a calibration processing section. The calibration processing section is configured to: set an initial stimulation current value as a starting stimulation current value; determine, as a current value variable process, one of a first and a second current value variable process; detect, as a first peak value and a second peak value, amplitude peak values of an electric signal; and detect a stimulation current value of a maximal stimulation of a subject, based on a result of a comparison of the first peak value and the second peak value, and acquires a stimulation current value that is obtained by adding a step current value to the stimulation current value, as the stimulation current value of a supramaximal stimulation of the subject.