Muscle Volume Profiling via Height-Mass Normalization

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Solution Overview

Problem

Current methods for assessing muscle adaptation in athletes are limited by their focus on individual muscles or small groups, failing to provide a comprehensive understanding of muscle hypertrophy patterns across the entire lower limb, which is crucial for understanding athletic performance.

Innovation Solution

A method and system that acquire image data from multiple muscles, calculate height-mass normalized muscle volumes, and identify deviations from reference values to detect muscle abnormalities or patterns, using rapid non-Cartesian MRI and image processing for comprehensive profiling.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If imaging modalities are used to measure muscle volume, then measurement precision is improved, but time consumption increases

Engineering Contradiction:
Improvemuscle volume measurementVSAvoidimaging and computation time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent segments the lower limb into multiple discrete muscle groups (quadriceps, hamstrings, calves, etc.) and measures each separately using MRI imaging. This segmentation allows comprehensive coverage of all muscles while maintaining efficient processing by focusing on specific anatomical regions rather than attempting to measure the entire limb as one unit.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent transforms raw MRI image data into standardized muscle volume parameters through automated image processing algorithms. By changing the parameter representation from complex image data to simplified volumetric measurements, the system achieves both high measurement precision and reduced computation time for clinical applications.

Inventive Principle:
Principle #35Parameter changes

2Quantity of substance

If comprehensive muscle assessment across entire lower limb is conducted, then measurement completeness is improved, but device complexity increases

Engineering Contradiction:
Improvenumber of muscles assessedVSAvoidimaging and processing system
Core Design Contradiction:
Quantity of substanceVSDevice complexity

Solution Approach 1:

The patent employs a universal MRI imaging protocol that can assess all lower limb muscles through a single standardized scanning procedure. The same imaging device and processing algorithm serve multiple functions: capturing images of different muscle groups, calculating volumes for various muscle types, and generating comprehensive profiles that cover the entire lower limb, thereby reducing the need for multiple specialized devices.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The patent creates standardized reference profiles of normal muscle volumes that serve as templates for comparison. These reference copies allow clinicians to assess patient muscle volumes by comparing against established norms, simplifying the interpretation process and reducing the complexity of real-time analysis while maintaining comprehensive assessment capabilities.

Inventive Principle:
Principle #26Copying

3Adaptability or versatility

If muscle volume data is normalized by height and mass, then comparability across subjects is improved, but calculation complexity increases

Engineering Contradiction:
Improvecross-subject comparabilityVSAvoiddata processing system
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent transforms raw muscle volume measurements into normalized parameters by dividing volume data by subject height and mass. This parameter transformation enables direct comparison between subjects of different sizes and demographics while the automated calculation process handles the mathematical complexity, making the normalization straightforward for clinical use.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent implements a feedback mechanism where normalized muscle volume data is continuously compared against reference ranges and population norms. This feedback loop allows the system to automatically identify deviations from normal patterns and provide interpretive guidance, reducing the need for manual analysis and simplifying the overall assessment process despite the added normalization calculations.

Inventive Principle:
Principle #23Feedback

Data Source

PatentEP3164069B1Systems and methods for identifying and profiling muscle patterns
Publication Date: 2020.09.16 UNIV OF VIRGINIA PATENT FOUND
  • EP3164069B1 patent drawingFigure 1
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  • EP3164069B1 patent drawingFigure 3

AI summary

Some aspects of the present disclosure relate to identifying and profiling muscle patterns. In one embodiment, a method includes acquiring image data associated with a selected muscle or group of muscles of one or more subjects and determining, based on the image data, muscle volume of the selected muscle or group of muscles. The method also includes calculating, based on the muscle volume and the height and mass of the one or more subjects, a height-mass normalized muscle volume for the selected muscle or group of muscles, and determining a deviation of the height-mass normalized muscle volume of the selected muscle or group of muscles from a mean value of muscle volume associated with a corresponding reference muscle or reference group of muscles. The method also includes identifying, based on the deviation, a muscle abnormality or absence of a muscle abnormality in the selected muscle or group of muscles.