MXene Electrodes for Neural Implants

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Solution Overview

Problem

Traditional implantable devices for recording and stimulating biological tissue face issues such as scarring, inflammation, degradation, and inadequate electrochemical properties, leading to high impedance and noise interference, which hinder long-term functionality and signal quality.

Innovation Solution

The use of MXene-based electrodes, which offer improved electrical conductivity, transparency, and flexibility, reducing electrochemical impedance and noise interference, and allowing for minimally invasive and high-resolution neural signal recording and stimulation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If traditional metal-based electrodes are used, then structural strength and mechanical stability are maintained, but electrochemical impedance is high and charge storage capacity is inadequate

Engineering Contradiction:
Improveelectrochemical performanceVSAvoidimpedance and noise
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent changes the material parameter from traditional metals to MXene (2D metal carbide), which fundamentally alters the electrochemical properties. MXene provides low electrochemical impedance and high charge storage capacity while maintaining mechanical stability, directly resolving the contradiction between structural strength and electrochemical performance

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent employs MXene as a composite material that combines the benefits of metal conductivity with two-dimensional material properties. This composite approach achieves both low impedance for good electrochemical performance and sufficient mechanical strength for implantable devices

Inventive Principle:
Principle #40Composite materials

2Reliability

If electrode size is increased to improve electrochemical properties, then charge storage capacity increases, but invasiveness and tissue damage increase

Engineering Contradiction:
Improveelectrochemical propertiesVSAvoidtissue invasiveness
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent changes the material composition to MXene, which provides superior charge storage capacity per unit area compared to traditional metals. This allows microscale electrodes to achieve adequate electrochemical properties without increasing size, thereby reducing tissue invasiveness

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent uses MXene's unique two-dimensional structure that mimics the surface area advantages of larger electrodes while maintaining the physical dimensions of microscale electrodes. This structural copying enables high charge storage capacity in a minimally invasive form factor

Inventive Principle:
Principle #26Copying

3Reliability

If metal or electroactive polymer coatings are added to improve electrochemical properties, then charge storage capacity increases, but toxic effects from electrode degradation increase

Engineering Contradiction:
Improveelectrochemical propertiesVSAvoidtoxic effects
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The patent extracts the electroactive functionality directly into the base MXene material rather than adding it through separate metal or polymer coatings. This eliminates the need for degradable coating layers that could release toxic byproducts, as MXene itself provides the desired electrochemical properties with improved biocompatibility

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent uses MXene as an intrinsically electroactive material that combines structural integrity with high charge storage capacity, replacing the need for composite coating structures. This single-material approach reduces the risk of toxic degradation products from multiple material interfaces and coatings

Inventive Principle:
Principle #40Composite materials

4Reliability

If traditional metal electrodes are used, then electrical conductivity is adequate, but optical transparency is blocked

Engineering Contradiction:
Improveelectrical conductivityVSAvoidoptical transparency
Core Design Contradiction:
ReliabilityVSIllumination intensity

Solution Approach 1:

The patent changes the material from bulk metal to two-dimensional MXene structure, which fundamentally alters optical properties. The 2D structure allows light to pass through while maintaining electrical conductivity, enabling both electrical and optical functionality in the same electrode material

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent transitions from three-dimensional bulk metal to two-dimensional MXene sheets. This dimensional reduction allows light to pass through the thin 2D structure while the extensive surface area maintains adequate electrical conductivity, resolving the contradiction between optical transparency and electrical performance

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Data Source

PatentUS11925466B2Implantable devices using 2D metal carbides and nitrides (MXenes)
Publication Date: 2024.03.12 DREXEL UNIV
  • US11925466B2 patent drawing
  • US11925466B2 patent drawing
  • US11925466B2 patent drawing

AI summary

An electrode, the electrode including an exposed contact surface, the exposed surface comprising a contact material, the contact material comprising a MXene. A device, the device including a plurality of electrodes, each of the plurality of electrodes comprising an exposed contact surface, the exposed surface comprising a contact material, the contact material comprising a MXene. A method, the method including delivering electrical stimulation to a subject with an electrode that comprises an exposed contact surface, the exposed contact surface comprising a contact material that includes a MXene.