Mycotoxin Sequestration Composition With Yeast-Clay Synergy
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Solution Overview
Problem
Current methods for mitigating mycotoxin contamination in animal feed are inadequate in effectively sequestering a wide range of mycotoxins, particularly emerging toxins, and often interfere with nutrient absorption or result in environmental pollution, while existing clay-based solutions are inefficient and non-biodegradable.
Innovation Solution
A co-mixture composition comprising yeast cell wall extracts, clay materials, and proteinaceous or cell wall extracts from bacterial or fungal fermentation processes, which synergistically adsorb and sequester mycotoxins in the animal's digestive tract, enhancing mycotoxin binding capacity and stability without interfering with nutrient absorption.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If clay-based materials are used to sequester mycotoxins, then mycotoxin binding capacity is improved, but nutrient absorption is interfered with and environmental pollution increases
Solution Approach 1:
The patent combines yeast cell wall extracts with clay materials to create a composite sequestering agent. The yeast cell wall components (beta-glucans, mannans) work synergistically with the clay to enhance mycotoxin binding while the organic nature of yeast cell walls prevents interference with nutrient absorption that characterizes pure clay-based solutions.
Solution Approach 2:
The patent modifies the chemical and physical parameters of clay materials by combining them with yeast cell wall extracts. This changes the surface properties and binding characteristics of the clay, enabling it to selectively bind mycotoxins without interfering with nutrient absorption in the animal digestive tract.
2Reliability
If clay-based materials are used to sequester mycotoxins, then mycotoxin binding capacity is improved, but environmental pollution increases
Solution Approach 1:
The patent changes the compositional parameters of the sequestering agent by incorporating biodegradable yeast cell wall materials. This transforms the clay from a non-biodegradable substance into a composite material that can break down environmentally, reducing pollution from manure and feed waste.
Solution Approach 2:
The patent converts the typically harmful effect of clay accumulation in the environment into a benefit by combining it with biodegradable yeast cell walls. The yeast component provides a biodegradable matrix that allows the clay to perform its mycotoxin-binding function while eventually breaking down naturally, turning a potential environmental hazard into an environmentally friendly solution.
3Object-generated harmful factors
If yeast cell wall extracts are used alone, then biodegradability is improved, but mycotoxin binding capacity is insufficient
Solution Approach 1:
The patent creates a composite material combining yeast cell wall extracts with clay materials. This composite leverages the biodegradability of yeast cell walls while incorporating the high mycotoxin binding capacity of clay, achieving both environmental friendliness and effective mycotoxin sequestration.
Solution Approach 2:
The patent merges two materials with complementary properties: yeast cell walls provide biodegradability and some binding capacity, while clay provides enhanced mycotoxin binding. The combination creates a synergistic effect where the total mycotoxin binding capacity exceeds what either material could achieve alone, while maintaining biodegradability.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The co-mixture composition achieves enhanced mycotoxin adsorption rates, up to 211% for deoxynivalenol and 285% for fusaric acid, while maintaining nutritional value and minimizing environmental impact, effectively reducing mycotoxin absorption and bioavailability in animals.
Implementation Method 1
These novel compositions and methods have shown synergistic properties in adsorption, sorption, sequestration, and binding of mycotoxins inside the digestive tract of animals
Implementation Method 2
These novel compositions and methods have shown synergistic properties in adsorption, sorption, sequestration, and binding of mycotoxins
Data Source
AI summary
The present disclosure relates to compositions and methods comprising a yeast cell wall extract and a clay material admixed to a proteinaceous and/or cell wall extract(s) from bacterial or fungal fermentation from amino acid production. In another embodiment, the present compositions comprise a yeast cell wall extract, a clay material, and an algal material admixed to a proteinaceous and/or cell wall extract(s) from bacterial or fungal fermentation from amino acid production. This disclosure also relates to methods of utilizing the same to sequester and/or adsorb mycotoxins internal or external to an animal, thereby reducing and/or preventing the toxic and harmful effects of mycotoxin contamination and/or infection in animals. Specifically, application of the present methods and compositions are found in the dietary administration and/or co-administration of the present compositions to animals in animal feed and/or animal production systems, as well as in therapeutic, prophylactic, and research applications.