Caffeine–NALT Liquid Composition for Stable High Concentrations
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Solution Overview
Problem
Existing caffeine formulations have low active ingredient concentrations, leading to single-dose consumption and safety concerns, with caffeine solubility decreasing from boiling to room temperature, and Rhodiola rosea ingestion methods being inconvenient and delayed.
Innovation Solution
A composition combining caffeine with N-Acetyl-L-Tyrosine (NALT) and Rhodiola rosea extract, where NALT increases caffeine solubility, maintaining high concentrations at room temperature, and includes a heating-mixing-cooling process to stabilize the solution.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Quantity of substance
If caffeine concentration is increased to provide sufficient energy-boosting effect, then the energy-boosting effect is improved, but safety concerns increase due to negative effects of caffeine on the body
Solution Approach 1:
N-Acetyl-L-Tyrosine acts as an intermediary substance that enables higher caffeine concentrations to be dissolved in water. The compound forms a complex with caffeine, increasing its solubility from 2g/100mL to over 10g/100mL at room temperature, thereby allowing sufficient energy-boosting effects without requiring unsafe concentrations of pure caffeine
2Quantity of substance
If caffeine is dissolved in boiling water to achieve high concentration, then caffeine solubility is improved, but the concentration decreases when the solution returns to room temperature
Solution Approach 1:
The invention changes the chemical parameters of the solution by introducing N-Acetyl-L-Tyrosine, which fundamentally alters caffeine's solubility characteristics. The compound forms a stable complex with caffeine that maintains high solubility across a wide temperature range, eliminating the precipitation problem that occurs when pure caffeine solutions cool down
3Reliability
If Rhodiola rosea is consumed in traditional forms (tincture, capsule, or pill), then the beneficial effects are provided, but the onset of effects is delayed and convenience is reduced
Solution Approach 1:
The invention replaces traditional solid dosage forms (capsules, pills) and slow-absorbing tinctures with a liquid oral spray formulation. This substitution of delivery mechanism enables rapid absorption through the oral mucosa, reducing the onset time from minutes to seconds while maintaining the beneficial effects of Rhodiola rosea
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The composition achieves stable, high caffeine concentrations suitable for convenient, efficient ingestion, mitigating caffeine's adverse effects and providing fast onset of Rhodiola rosea's benefits.
Implementation Method 1
tyrosine or NALT, (e.g. in some cases, to accelerate the reaction, preferably when exposed to heat), reacts with caffeine, substantially increasing caffeine's solubility
Implementation Method 2
to accelerate the reaction, preferably when exposed to heat
Implementation Method 3
the concentration of caffeine found in the solution including tyrosine or NALT remains elevated even when the solution returns to room temperature
Data Source
AI summary
A liquid composition for use as a consumable stimulant; it has a consumable liquid solvent comprising water; caffeine at a concentration of at least 0.04 g/mL once dissolved in the consumable liquid solvent; and a tyrosine-based compound, wherein the presence of the tyrosine-based compound results in an increased solubility of the caffeine in the consumable liquid solvent. A method of increasing the solubility of caffeine.