Nano-Calcium Carbonate Composition for Osteoporosis Treatment
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Solution Overview
Problem
Current calcium carbonate formulations have low absorption rates, making them ineffective in preventing and treating osteoporosis, and there is a need for a cost-effective and absorbable calcium source that avoids animal-derived materials.
Innovation Solution
A calcium carbonate composition is manufactured by dispersing calcium, magnesium, and zinc in water, followed by carbon dioxide treatment to form nano-sized microparticles, with specific ratios of magnesium and zinc to enhance absorption, and the addition of dispersants and emulsifiers to maintain particle size and dispersive power.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If calcium carbonate is used as a calcium supplement, then cost is reduced, but absorption rate is noticeably low
Solution Approach 1:
The patent combines calcium carbonate with magnesium and zinc in specific ratios (0.015-0.8 parts magnesium and 0.015-0.45 parts zinc per 100 parts calcium) to create a composite material that enhances absorption while maintaining cost-effectiveness. This composite approach resolves the contradiction by improving absorption rate through synergistic effects of multiple minerals without significantly increasing manufacturing cost.
Solution Approach 2:
The patent changes the particle size parameter of calcium carbonate to nano-level dimensions, which dramatically improves absorption rate. By modifying this physical parameter, the invention achieves high absorption effectiveness while still using cost-effective calcium carbonate as the base material rather than expensive alternatives like calcium gluconate.
2Reliability
If animal materials such as eggshells and cow bones are used as natural calcium, then calcium content is high, but infectious diseases may be transmitted from animals to humans
Solution Approach 1:
The patent replaces animal-derived calcium sources with synthetic calcium carbonate, which is safer and more controllable. While animal materials have high calcium content, they pose safety risks. The invention uses inexpensive, safe calcium carbonate combined with magnesium and zinc to achieve effective calcium supplementation without the risk of zoonotic disease transmission.
3Reliability
If calcium carbonate particles are made larger for easier manufacturing, then manufacturing is simplified, but absorption rate decreases
Solution Approach 1:
The patent changes the particle size parameter to nano-level dimensions through controlled carbonatization processes. This parameter change dramatically improves absorption rate while the manufacturing process remains relatively simple, involving dispersing calcium, magnesium, and zinc in water, supplying carbon dioxide gas, and drying. The nano-sized microparticles are formed naturally through the carbonatization reaction without requiring complex nanotechnology equipment.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The composition significantly increases calcium absorption, effectively preventing and treating osteoporosis, as demonstrated by enhanced bone strength and calcium content in experimental models.
Implementation Method 1
supplying a carbon dioxide gas to the mixture after step (A)... calcium carbonate microparticles may be formed by carbonatizing calcium by supplying the carbon dioxide gas
Implementation Method 2
producing a mixture by dispersing calcium, magnesium, and zinc in water
Data Source
AI summary
The present invention relates to a calcium carbonate composition for ameliorating, preventing and treating osteoporosis, and a manufacturing method therefor. More specifically, the present invention relates to a calcium carbonate composition for alleviating, preventing and treating osteoporosis, the composition comprising calcium, magnesium and zinc, and having calcium carbonate microparticles formed by the supply of carbon dioxide gas. The present invention provides a composition for maximizing the absorption of calcium, the composition being developed as a health food, food material or the like, and displaying the effects of relieving and alleviating illnesses and symptoms caused by a lack of calcium.