Nanobubble Antiparasitic Treatment for Uniform Fish Parasite Control

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Solution Overview

Problem

Current treatments for parasitic diseases in fish farming, particularly those caused by monogeneans and gill parasites, are labor-intensive, stressful for the fish, and have variable effectiveness due to logistical challenges and parasite sensitivity.

Innovation Solution

The use of nanobubbles in conjunction with antiparasitic agents enhances treatment efficacy by improving agent distribution, solubility, and stability, ensuring uniform dispersion and increased contact with parasites.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If traditional antiparasitic treatments are used, then parasite removal is achieved, but treatment coverage and efficacy are insufficient due to poor distribution and solubility

Engineering Contradiction:
Improvetreatment efficacyVSAvoidtreatment coverage
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

Nanobubbles serve as an intermediary carrier that enhances the distribution and contact of antiparasitic agents with ectoparasites. The nanobubbles act as a mediator between the treatment solution and the parasite, improving both coverage and efficacy through their unique surface properties and ability to penetrate boundary layers.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The invention changes the physical parameters of the treatment system by introducing nanoscale bubbles with specific surface charge and volume characteristics. These parameter changes enable superior dispersion, solubility, and stability of the antiparasitic agents, leading to enhanced treatment coverage and efficacy.

Inventive Principle:
Principle #35Parameter changes

2Reliability

If high-concentration treatments are applied, then parasite removal effectiveness increases, but fish stress and labor intensity increase

Engineering Contradiction:
Improveparasite removal effectivenessVSAvoidfish stress
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

Nanobubbles act as a intermediary that delivers antiparasitic agents to parasites without requiring high concentrations in the bulk solution. The nanobubbles concentrate the active agents at the interface where they contact parasites, maintaining effectiveness while reducing overall treatment stress on fish.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The invention applies local quality by concentrating the antiparasitic action at the nanobubble- parasite interface rather than relying on high bulk concentrations. This localized delivery mechanism maintains high effectiveness at the point of contact while keeping the overall treatment environment gentle for the fish.

Inventive Principle:
Principle #3Local quality

3Ease of operation

If traditional immersion baths are used, then treatment is applied to the fish, but labor intensity and operational complexity increase

Engineering Contradiction:
Improvetreatment applicationVSAvoidtreatment system complexity
Core Design Contradiction:
Ease of operationVSDevice complexity

Solution Approach 1:

The nanobubble system provides self-service by automatically dispersing and distributing antiparasitic agents throughout the treatment bath without requiring complex mechanical agitation or multiple application stages. The nanobubbles naturally distribute themselves and maintain contact with parasites through their inherent physical properties.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

By changing the physical state and surface properties of the treatment medium through nanobubble generation, the system simplifies operation. The nanobubbles provide self-sustaining distribution and stability, eliminating the need for complex dosing mechanisms or multiple treatment stages.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Nanobubbles improve the efficacy of antiparasitic treatments by enhancing parasite removal and treatment coverage, leading to more complete control of ectoparasites.

Implementation Method 1

nanobubbles improve the distribution of antiparasitic agents, enhancing contact with ectoparasites. In addition, nanobubbles increase the solubility and stability of antiparasitic agents

Methodology Applied
Scientific EffectNanobubble dispersion: Dispersion (of waves)

Implementation Method 2

The small size and surface charge of nanobubbles also help disperse the antiparasitic solution uniformly, increasing treatment coverage and efficiency

Methodology Applied
Scientific EffectSurface charge interaction: Electrostatics

Implementation Method 3

using nanobubbles in conjunction with antiparasitic agents enhances the removal of parasites. The unique properties of nanobubbles increase the efficacy of these treatments

Methodology Applied
Scientific EffectPhysical removal enhancement:

Data Source

PatentUS20260021054A1Methods and compositions for treating parasitic diseases using nanobubbles and Anti-parasitic agents
Publication Date: 2026.01.22 MOLEAER INC

AI summary

Provided herein are methods and compositions for treating parasitic diseases using nanobubbles in combination with at least one anti-parasitic agent.