Nanodiamond Denture Composite for Candida-Resistant Surfaces

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Solution Overview

Problem

Denture stomatitis, primarily caused by Candida albicans, is a significant problem for individuals wearing dentures, with conventional treatments being ineffective or causing adverse effects, and existing antimicrobial agents leading to resistance and toxicity issues.

Innovation Solution

A dental composite material containing nanodiamonds is developed to inhibit Candida albicans attachment to dentures, reducing surface roughness without increasing hydrophobicity, thereby preventing denture stomatitis.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of manufacture

If conventional acrylic resin is used for denture bases, then ease of construction and repair is improved, but surface roughness increases leading to Candida albicans colonization

Engineering Contradiction:

Improveease of constructionVSAvoidsurface roughness

Core Design Contradiction:

Ease of manufactureVSObject-affected harmful factors

Solution Approach 1:

The patent applies composite materials by combining acrylic resin with nanodiamonds and silver nanoparticles. The nanodiamonds (0.1-5 wt%) provide surface smoothness reduction while silver nanoparticles (0.01-1 wt%) provide antimicrobial activity. This composite approach allows the denture base to maintain ease of construction from acrylic resin while eliminating the harmful surface roughness and Candida colonization issues through the synergistic effects of the nanomaterial additives.

Inventive Principle:

Principle #40Composite materials

2Object-affected harmful factors

If antimicrobial agents are incorporated in denture base material, then Candida adhesion is reduced, but toxic side effects occur

Engineering Contradiction:

ImproveCandida adhesionVSAvoidtoxic side effects

Core Design Contradiction:

Object-affected harmful factorsVSObject-generated harmful factors

Solution Approach 1:

The patent applies parameter changes by using nanoscale dimensions (1-100 nm) for both nanodiamonds and silver nanoparticles. This nanoscale parameter change provides enhanced surface area-to-volume ratio for improved antimicrobial efficacy at extremely low concentrations (0.01-1 wt% silver nanoparticles), reducing the risk of toxic side effects. The nanodiamonds further modify surface parameters to reduce hydrophobicity, creating a surface that is inherently less favorable for Candida adhesion without requiring high concentrations of antimicrobial agents.

Inventive Principle:

Principle #35Parameter changes

3Object-affected harmful factors

If chemical disinfection is performed, then Candida is eliminated, but surface roughness and color changes occur

Engineering Contradiction:

ImproveCandida eliminationVSAvoidsurface roughness

Core Design Contradiction:

Object-affected harmful factorsVSManufacturing precision

Solution Approach 1:

The patent applies preliminary action by incorporating nanodiamonds and silver nanoparticles into the denture base material during manufacturing, before the denture is delivered to the patient. This pre-establishment of antimicrobial properties and surface smoothness eliminates the need for aggressive post-manufacturing chemical disinfection that would cause surface roughness and color changes. The nanocomposite material provides built-in, long-lasting protection that maintains surface integrity over time.

Inventive Principle:

Principle #10Preliminary action

4Strength

If denture surfaces are made hydrophobic, then material properties are improved, but Candida albicans attachment increases

Engineering Contradiction:

Improvematerial propertiesVSAvoidCandida attachment

Core Design Contradiction:

StrengthVSObject-affected harmful factors

Solution Approach 1:

The patent applies parameter changes by modifying surface energy characteristics through nanodiamond incorporation. The nanodiamonds alter the surface chemistry and topography at the nanoscale, reducing hydrophobicity and creating a surface that is less favorable for Candida albicans attachment. This parameter change in surface wettability is achieved while maintaining the bulk material strength and structural properties of the acrylic resin denture base.

Inventive Principle:

Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The incorporation of nanodiamonds significantly reduces Candida albicans adhesion and improves surface smoothness, effectively addressing denture stomatitis while maintaining the mechanical properties of the denture material.

Implementation Method 1

Incorporation of nanodiamonds into polymethylmethacrylate (PMMA) dental composite materials to reduce Candida albicans adhesion, improving surface smoothness

Methodology Applied

Scientific EffectNanocomposite reinforcement: Composite Materials

Implementation Method 2

The nanodiamond-reinforced PMMA composite significantly decreases Candida albicans adhesion

Methodology Applied

Scientific EffectAdsorption: Adsorption

Data Source

PatentUS12611290B2Method for forming and polishing a composite denture

Publication Date: 2026.04.28 IMAM ABDULRAHMAN BIN FAISAL UNIV

AI summary

A curable composite material containing nanodiamonds, denture bases and other dental prosthetics made from the composite material and methods for treating dental stomatitis using these prosthetics.