Nanoparticle ATP Extraction for Airborne Pathogen Detection

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Existing pathogen detection methods in air face challenges with short signal duration and high costs due to manual operation and additional factors required for measurement.

Innovation Solution

A pathogen detection method using nanoparticles formed in a chamber, which collide with pathogens to extract adenosine triphosphate (ATP), followed by collection and detection of a light-emitting reaction, reducing the need for manual operation and additional reagents.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If manual operation and additional factors are used for pathogen detection, then measurement capability is improved, but device complexity and cost increase

Engineering Contradiction:
Improvepathogen detection capabilityVSAvoiddevice complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent extracts the essential detection function by using nanoparticles to directly collide with and extract ATP from pathogens, eliminating the need for complex manual operations and additional reagents. The collector extracts pathogens having collided with nanoparticles, and the sensor detects the light-emitting reaction from ATP, achieving simplified pathogen detection.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The nanoparticles automatically collide with pathogens and extract ATP without manual intervention. The system performs self-service detection where the collector automatically collects collided pathogens and the sensor automatically detects the light-emitting reaction, eliminating manual operations while maintaining detection capability.

Inventive Principle:
Principle #25Self-service

2Measurement precision

If manual operation is performed for each measurement, then measurement accuracy is improved, but productivity decreases

Engineering Contradiction:
Improvemeasurement accuracyVSAvoidmeasurement efficiency
Core Design Contradiction:
Measurement precisionVSProductivity

Solution Approach 1:

The detection system performs automatic pathogen detection through self-service operations. Nanoparticles automatically collide with pathogens in the air, the collector automatically collects the collided pathogens, and the sensor automatically detects the light-emitting reaction from extracted ATP, eliminating manual operations and significantly improving measurement efficiency.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The system enables continuous pathogen detection by maintaining a steady flow of nanoparticles that continuously collide with pathogens in the air. The collector and sensor operate continuously to collect and detect pathogens, eliminating the need for repeated manual measurements and improving overall productivity.

Inventive Principle:
Principle #20Continuity of useful action

3Measurement precision

If additional reagents and manual operations are used, then detection sensitivity is improved, but cost increases

Engineering Contradiction:
Improvedetection sensitivityVSAvoidcost
Core Design Contradiction:
Measurement precisionVSQuantity of substance

Solution Approach 1:

The patent extracts ATP directly from pathogens through nanoparticle collision, eliminating the need for additional reagents and manual extraction procedures. This direct extraction method maintains high detection sensitivity while significantly reducing the cost associated with multiple reagents and manual operations.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The system uses nanoparticles as disposable, low-cost elements for pathogen detection. The nanoparticles perform their function of colliding with and extracting ATP from pathogens, then are discarded, replacing expensive and complex reagent systems while maintaining detection sensitivity.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables easier and cost-effective pathogen detection in air by utilizing nanoparticles to extract ATP from pathogens, facilitating quick and sensitive measurement without manual labor or special reagents.

Implementation Method 1

extracting adenosine triphosphate (ATP) by causing the nanoparticles to collide with pathogens

Methodology Applied
Scientific EffectCollision: Impact Force

Implementation Method 2

detecting a light-emitting reaction formed by a reaction with the ATP

Methodology Applied
Scientific EffectLight-emitting reaction: Chemiluminescence

Data Source

PatentUS20220082555A1Pathogen detection method and apparatus
Publication Date: 2022.03.17 UI (UNIVERSITY IND FOUNDATION) YONSEI UNIVERSITY
  • US20220082555A1 patent drawing
  • US20220082555A1 patent drawing
  • US20220082555A1 patent drawing

AI summary

A pathogen detection method includes forming nanoparticles, extracting adenosine triphosphate (ATP) by causing the nanoparticles to collide with pathogens, collecting the pathogens having collided with the nanoparticles, and detecting a light-emitting reaction formed by a reaction with the ATP.