Nanoparticle Hydroxyapatite Coating for Tooth Surface Repair

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Solution Overview

Problem

Existing tooth surface treatment agents using hydroxyapatite particles face issues with agglomeration, leading to non-uniform, weak, and short-lived layers on the tooth surface.

Innovation Solution

A tooth surface treatment agent comprising a liquid with a pH of 1.0 to 3.0, containing an organic acid and hydroxyapatite particles with a particle diameter of 200 nm or less, which stabilizes the particles and forms a uniform, high-strength apatite layer.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If hydroxyapatite particles are used in tooth surface treatment agents, then the treatment can restore tooth surfaces, but the particles agglomerate when made into solution or paste, resulting in non-uniform layers with poor strength and durability

Engineering Contradiction:
Improvelong-term durability of tooth surface restorationVSAvoiduniformity of hydroxyapatite particle dispersion
Core Design Contradiction:
ReliabilityVSStability of the object's composition

Solution Approach 1:

The patent changes the particle size parameter of hydroxyapatite to 200 nm or less (nanoparticle scale), which fundamentally alters the dispersion behavior and prevents agglomeration. It also changes the pH parameter to 1.0-3.0, creating an acidic environment that stabilizes the nanoparticle dispersion. These parameter changes resolve the contradiction by enabling both uniform dispersion and long-term durability.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent introduces an intermediary acidic liquid environment (pH 1.0-3.0) that mediates between the hydroxyapatite particles and the tooth surface. This intermediary medium prevents particle agglomeration while facilitating uniform deposition, thereby resolving the contradiction between dispersion stability and restoration reliability.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Manufacturing precision

If hydroxyapatite particles are finely milled to prevent agglomeration, then particle dispersion improves, but the particles still agglomerate without proper stabilizing medium

Engineering Contradiction:
Improveparticle size control and uniformityVSAvoidparticle dispersion stability
Core Design Contradiction:
Manufacturing precisionVSStability of the object's composition

Solution Approach 1:

The patent sets the particle size parameter at 200 nm or less and the pH parameter at 1.0-3.0, creating optimal conditions where fine particles remain dispersed without agglomeration. This dual parameter control resolves the contradiction by ensuring both manufacturing precision and dispersion stability.

Inventive Principle:
Principle #35Parameter changes

3Ease of manufacture

If conventional hydroxyapatite treatment is applied, then the tooth surface can be treated, but the formed layer is non-uniform and weak

Engineering Contradiction:
Improvesimplicity of treatment applicationVSAvoidstrength of formed apatite layer
Core Design Contradiction:
Ease of manufactureVSStrength

Solution Approach 1:

The patent changes the particle size to 200 nm or less and pH to 1.0-3.0, which transforms the application process into a simple涂布 (coating) operation that forms uniform, high-strength layers. The nanoparticle size and acidic pH work together to enable easy application while achieving superior layer strength, resolving the contradiction between ease of manufacture and layer strength.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution achieves a uniform, high-strength apatite layer that effectively covers minute recesses on the tooth surface, providing excellent long-term durability and resistance.

Implementation Method 1

a liquid with a pH of 1.0 to 3.0, containing an organic acid

Methodology Applied
Scientific EffectDissolution: Solvation

Implementation Method 2

the surface treatment agent reacts on the tooth surface to form a layer covering the entire tooth including the minute recesses

Methodology Applied
Scientific EffectDeposition: Deposition (physical)

Implementation Method 3

hydroxyapatite particles will agglomerate if the dispersing medium is not configured to stabilize hydroxyapatite particles

Methodology Applied
Scientific EffectDispersion stabilization: Dispersion (of waves)

Data Source

PatentUS20250082553A1Tooth Surface Treating Agent and Tooth Surface Treating Kit
Publication Date: 2025.03.13 NISHIO
  • US20250082553A1 patent drawing
  • US20250082553A1 patent drawing

AI summary

The present invention provides a tooth surface treatment agent and a tooth surface treatment kit to form a uniform, high-strength layer composed of apatite on tooth surface and to repair minute recesses on the tooth surface.The tooth surface treatment agent includes: a liquid with a pH of 1.0 to 3.0 containing an organic acid; and hydroxyapatite particles with a particle diameter of 200 nm or less. The tooth surface treatment kit includes: a first treatment agent that is a liquid having a pH of 1.0 to 3.0 and containing an organic acid, which is accommodated in a first container; and a second treatment agent including hydroxyapatite particles having a particle diameter of 200 nm or less, which is accommodated in a second container different from the first container. The tooth treatment agent is prepared by mixing the first and second treatment agents, and is applied to the tooth surface.