Napped Coated Wound Dressing for Hemostasis
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Existing hemostatic patches lack good tissue adhesion properties and effective coating penetration due to their low surface area and stiffness, which hampers their ability to control bleeding effectively.
Innovation Solution
A melt-blown substrate with a napped surface is used to create a high-surface-area, low-profile hemostatic patch that enhances tissue adhesion and coating penetration, achieved through a process of napping that loosens fibers and increases matrix loft, allowing for better integration of cross-linkable active molecules.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If a conventional hemostatic patch is used, then the basic hemostatic function is provided, but the tissue adhesion properties are poor and coating penetration is ineffective
Solution Approach 1:
The patent applies napping treatment to the substrate surface, which raises fibers from the flat surface into the third dimension, creating a three-dimensional napped surface structure. This dimensional transformation increases the effective surface area available for coating application and enhances tissue adhesion by providing mechanical interlocking capability between the coating layer and the substrate.
Solution Approach 2:
The napped substrate creates a porous surface structure with increased surface area and void spaces between raised fibers. This porous structure allows coating materials to penetrate deeper into the substrate, improving coating penetration effectiveness and enabling better integration of hemostatic agents with the substrate matrix.
2Strength
If the substrate is made stiff for structural integrity, then the patch maintains its shape, but coating penetration and tissue conformability are reduced
Solution Approach 1:
The patent applies napping treatment only to the surface layer of the substrate while maintaining the bulk substrate structure intact. This creates a local quality difference where the surface becomes soft, porous, and compliant for tissue conformability, while the underlying bulk substrate retains its structural integrity and strength. The gradient structure allows simultaneous achievement of both stiffness and flexibility.
3Ease of manufacture
If the surface is left flat for simple manufacturing, then the production process is straightforward, but coating penetration and surface roughness are insufficient
Solution Approach 1:
The patent employs a mechanical napping process that uses controlled abrasion or needle penetration to raise surface fibers. This mechanical treatment creates the desired three-dimensional surface structure and porosity without requiring complex chemical treatments or multi-step manufacturing processes, maintaining relative manufacturing simplicity while significantly improving coating penetration speed and effectiveness.
Data Source
Figure 1
Figure 2
Figure 3
AI summary
The present invention is directed to an absorbable hemostatic patch that utilizes a biocompatible fibrous, fabric substrate that is melt-blown and napped or loosened at the surface, with the substrate having a low-profile, high flexibility, strength and porosity that is suitable for coating cross-linkable active molecules and ultimately effective for use as a hemostat in situations of problematic bleeding.