Single-Use Nasal Delivery Device with Unit Dose Propellant
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Solution Overview
Problem
Current nasal drug delivery devices require patients or caregivers to coordinate breath with device actuation, leading to ineffective drug delivery, especially for inexperienced users, and often necessitate a priming step that can affect efficacy and dosing accuracy.
Innovation Solution
A single-use nasal drug delivery device utilizing a unit dose propellant canister that is actuated via a simple mechanism, eliminating the need for breath coordination and priming, ensuring consistent and reproducible medication delivery with a single actuation step.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If a multi-use nasal delivery device is used, then the device can be reused for multiple dosing, but it increases the risk of inadvertent overdosing and misuse
Solution Approach 1:
The device is segmented into separate single-use components: a reusable housing body and disposable cartridges containing both medication and propellant. This segmentation ensures that each dose is self-contained and cannot be reused, eliminating overdosing risks while keeping the overall system relatively simple through modular design.
Solution Approach 2:
The patent employs disposable cartridges that contain a single dose of medication and a unit dose of propellant. These cartridges are designed for single use only and are discarded after one administration, ensuring dosing accuracy by preventing any possibility of reuse or overdosing, while the low cost of the disposable component makes this approach economically viable.
2Manufacturing precision
If a unit dose container of propellant is used, then consistent and controlled propellant delivery is achieved, but the device requires a more complex actuation mechanism
Solution Approach 1:
The patent merges the medication container and propellant container into a single integrated cartridge assembly. Both the medication reservoir and the unit dose propellant container are housed together in one disposable unit, simplifying the actuation mechanism by eliminating the need for separate propellant filling and dosing steps, while still maintaining precise dosing through the pre-measured unit dose propellant.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The device provides intuitive and reliable medication delivery to the nasal cavity, reducing the risk of overdosing and misuse, as it uses a propellant to propel medication directly into the nasal cavity without requiring user coordination or priming, ensuring consistent dosing.
Implementation Method 1
a propellant canister containing a propellant capable of propelling the compound to a nasal cavity of a user
Implementation Method 2
The puncture element may be positioned to puncture the propellant canister, which causes the release of the propellant from the propellant canister
Implementation Method 3
a diffuser positioned between the propellant canister and the dose holding chamber such that the diffuser diffuses the propellant upon its release from the propellant canister
Data Source
AI summary
Embodiments relate to a single-use device for delivery of medication into a nasal cavity. In an embodiment, the device includes a propellant canister containing a propellant capable of propelling the compound to the nasal cavity. The propellant canister is displaceable between an unactuated position and an actuated position within the device. The device further includes an actuation element with an actuation lever configured to displace the propellant canister from the unactuated position to the actuated position. The device also includes a puncture element positioned to puncture the propellant canister, which causes the release of the propellant from the propellant canister. The device further includes a dose holding chamber containing a unit dose of the compound. The dose holding chamber is positioned such that propellant flows into the dose holding chamber and causes the compound to be propelled from the dose holding chamber to the nasal cavity of the user.