Native Leaflet Position Analysis for Coronary Re-Access

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Solution Overview

Problem

Existing methods fail to accurately determine access to coronary arteries after prosthetic valve implantation due to displacement of native leaflets, leading to potential blockage and unsuccessful re-access procedures.

Innovation Solution

Analyze pre- and post-procedure images to determine the position of mineral deposits on native leaflets and the prosthetic valve, estimating the native leaflet position post-implantation, and assessing access to coronary arteries based on this information.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If prosthetic valve is implanted at native valve, then aortic valve stenosis is treated, but native leaflet displacement blocks access to coronary arteries

Engineering Contradiction:
Improveaortic valve stenosis treatmentVSAvoidcoronary artery access
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The system performs preliminary analysis of pre-procedure images to identify mineral deposit positions on native leaflets before implantation. This advance characterization allows prediction of post-implantation leaflet displacement and assessment of potential coronary artery blockage, enabling preventive planning for re-access procedures.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system uses mineral deposits as intermediary markers to indirectly determine native leaflet positions. Since mineral deposits remain visible and identifiable through imaging, they serve as reference points to track leaflet displacement caused by prosthetic valve implantation, enabling assessment of coronary access without direct visualization.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Device complexity

If native leaflet position is not determined, then procedure is simpler, but access to coronary arteries cannot be assessed

Engineering Contradiction:
Improveposition determination systemVSAvoidcoronary artery access assessment
Core Design Contradiction:
Device complexityVSReliability

Solution Approach 1:

The system creates a virtual copy or representation of the native valve anatomy using pre-procedure imaging data. By analyzing mineral deposit positions in the pre-procedure image and correlating them with anatomical references, the system reconstructs the spatial relationship between native leaflets and coronary arteries, enabling accurate access assessment.

Inventive Principle:
Principle #26Copying

Solution Approach 2:

The system replaces direct mechanical measurement or visualization of native leaflet positions with an imaging-based analytical approach. By using computational analysis of mineral deposit locations in pre- and post-procedure images, the system determines leaflet displacement without requiring direct mechanical intervention or complex surgical instrumentation.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Measurement precision

If pre-procedure images are analyzed, then native leaflet position can be determined, but additional imaging and analysis time is required

Engineering Contradiction:
Improvenative leaflet position determinationVSAvoidimaging and analysis time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The system performs all necessary position determination and access assessment using pre-procedure images before the implantation procedure. By completing the analytical work in advance, the actual surgical procedure can proceed more efficiently without time-consuming intraoperative imaging or analysis, though pre-procedure imaging time is required.

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS20250352160A1Systems and methods for anatomical feature determination
Publication Date: 2025.11.20 EDWARDS LIFESCIENCES CORP
  • US20250352160A1 patent drawing
  • US20250352160A1 patent drawing
  • US20250352160A1 patent drawing

AI summary

Techniques for determining a position of a native leaflet can include identifying a position of a mineral formation on the native leaflet before implantation of a prosthetic valve and analyzing an image representing the prosthetic valve implanted within the cardiac vessel. The analysis can identify a position of the mineral formation within the cardiac vessel after the prosthetic valve is implanted. Based on the position of the mineral formation on the native leaflet before implantation of the prosthetic valve and the position of the mineral formation within the cardiac vessel, a position of the native leaflet within the cardiac vessel can be determined.