Natural Complex Extract Composition for Synergistic Skin Benefits
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Solution Overview
Problem
Current compositions lack effective solutions for antioxidation, immune enhancement, skin whitening, collagenase inhibition, and anti-wrinkle effects while maintaining low cytotoxicity, particularly in natural product-based formulations.
Innovation Solution
A composition comprising a natural complex extract of goji berry, fig, and Korean mint or goji berry and persimmon leaf, using hot water extraction and purification methods to create a synergistic blend for antioxidation, immune enhancement, skin whitening, collagenase inhibition, and anti-wrinkle effects, with the option of incorporating a pharmaceutically acceptable carrier for pharmaceutical compositions or using as food additives and cosmetics.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If natural product extracts are used for antioxidation and immune enhancement, then health benefits are improved, but cytotoxicity may increase
Solution Approach 1:
The patent combines multiple natural extracts (goji berry, fig, Korean mint, and persimmon leaf) into a composite formulation. This merging approach allows the synergistic effects of different plant components to enhance health benefits while distributing and diluting potential cytotoxic substances across multiple sources, thereby reducing overall cytotoxicity compared to single-source extracts.
Solution Approach 2:
The patent optimizes extraction parameters including solvent type (water, alcohol, or their mixtures), extraction temperature (60-100°C), and extraction time (1-24 hours) to maximize beneficial compounds while minimizing cytotoxic substances. By controlling these parameters, the formulation achieves high antioxidant and immune-enhancing activity with reduced cytotoxicity.
2Reliability
If multiple plant extracts are combined for synergistic effects, then antioxidation and immune enhancement are improved, but formulation complexity increases
Solution Approach 1:
The patent develops a universal extraction and formulation system that can accommodate multiple plant extracts using the same basic protocol. The standardized method involving solvent selection, extraction conditions, and formulation steps allows for easy incorporation of different plant materials (goji berry, fig, Korean mint, persimmon leaf) without requiring separate processing procedures, thereby managing formulation complexity while achieving synergistic effects.
3Quantity of substance
If hot water extraction is used to maximize extract yield, then active ingredient concentration is improved, but extraction time and energy consumption increase
Solution Approach 1:
The patent optimizes hot water extraction parameters including temperature (60-100°C), time (1-24 hours), and solvent-to-material ratio to achieve maximum extract yield with reasonable energy consumption. By identifying the optimal parameter combination, the system maximizes active ingredient concentration while minimizing excessive energy input and extraction time.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The composition demonstrates excellent antioxidative, immune-enhancing, whitening, collagenase-inhibiting, and anti-wrinkle effects through synergistic action, with low cytotoxicity, as shown by various test results, including high antioxidant activity, cell viability, and reduced melanin and MMP-1 gene expression.
Implementation Method 1
using hot water extraction and purification methods to create a synergistic blend
Implementation Method 2
reduced melanin and MMP-1 gene expression
Implementation Method 3
collagenase-inhibiting effects
Data Source
AI summary
The present invention relates to a composition comprising a natural complex extract. It is confirmed that the composition has synergistic effects on antioxidant activity, immune enhancement, whitening, anti-wrinkle and collagenase inhibition with low cytotoxicity, and therefore, the composition is suitable for uses of antioxidation, immune, whitening and skin anti-wrinkle.