Needle Biopsy Target Localization Using 3D Marker Pair Imaging

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Solution Overview

Problem

Small lesions, such as those less than 10 mm in size, are difficult to accurately diagnose using typical imaging devices, leading to inaccuracies in needle biopsy sampling locations, which can result in inadequate tissue sampling for disease diagnosis.

Innovation Solution

A method and system for determining a target point for a needle biopsy using a computing device that involves obtaining and labeling pairs of markers on localization images, generating visualized data, and selecting a target point based on these markers to ensure accurate sampling.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If typical imaging devices are used for small lesions, then the imaging process is simple, but the diagnosis accuracy deteriorates

Engineering Contradiction:
Improvediagnosis accuracyVSAvoidimaging system complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent introduces markers as intermediary objects that are placed on or near the lesion. These markers serve as reference points that can be clearly visualized by the imaging device, enabling precise localization of the small lesion without requiring the imaging device itself to be more complex. The markers act as a mediator between the limited imaging capability and the need for high diagnostic accuracy.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent transforms the 2D imaging problem into a 3D localization problem by introducing spatial coordinates and multiple imaging angles. By acquiring images from different angles and reconstructing 3D positions of markers and lesions, the system achieves higher diagnostic accuracy for small lesions while maintaining relatively simple imaging devices.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Measurement precision

If multiple localization images are acquired for marker positioning, then the target point determination accuracy is improved, but the time consumption increases

Engineering Contradiction:
Improvetarget point determination accuracyVSAvoidtime consumption
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent performs preliminary actions by pre-placing markers on the lesion before the biopsy procedure. The markers are positioned in advance and their locations are recorded in the localization images. This preliminary positioning eliminates the need for time-consuming real-time tracking during the biopsy, as the target point can be directly determined from the pre-acquired images with marker positions already established.

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS12496132B2System and method for determining a target point for a needle biopsy
Publication Date: 2025.12.16 SHANGHAI UNITED IMAGING HEALTHCARE
  • US12496132B2 patent drawing
  • US12496132B2 patent drawing
  • US12496132B2 patent drawing

AI summary

A system and a method for determining a target point for a needle biopsy may be provided. The method may include obtaining a first localization image and a second localization image regarding a region of interest (ROI) of a subject. The method may include labelling a plurality of pairs of markers for the ROI on the first localization image and the second localization image. The method may include determining a space position of each of the plurality of pairs of markers. The method may include generating visualized data regarding the ROI based on the space positions of the plurality of pairs of markers, and determining the target point for the needle biopsy based on the visualized data.