Needle Probe Resistive Heating for Real-Time Tissue Sensing

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Solution Overview

Problem

Existing methods for measuring tissue properties in medical applications are complex and time-consuming, making it difficult for surgeons to obtain real-time information during operations, and there is a need for efficient methods to assess food freshness and product condition without opening containers.

Innovation Solution

A needle probe with a resistive element that applies heating and measures electrical responses to determine compositional information, using simple electronics for quick and accurate analysis of thermal properties, including detection of metallic and magnetic nanoparticles.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If complex existing methodologies are used to measure tissue properties, then measurement precision can be maintained, but device complexity and time consumption increase significantly

Engineering Contradiction:
Improvetissue property measurement accuracyVSAvoidmeasurement system complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent extracts the essential measurement function from complex existing methodologies by using a simple needle probe with a single electrode that measures electrical properties directly at the tissue site. This eliminates the need for complex laboratory equipment and sample processing systems while maintaining measurement accuracy through direct in-situ sensing.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent replaces complex mechanical and chemical analysis systems with an electrical measurement system. Instead of using complex physical dissection and chemical analysis methods, the invention uses electrical impedance and capacitance measurements to detect tissue properties, significantly simplifying the measurement apparatus.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Loss of information

If biopsies are sent away for analysis using existing techniques, then compositional information can be obtained, but time consumption increases significantly

Engineering Contradiction:
Improvecompositional information availabilityVSAvoidanalysis time
Core Design Contradiction:
Loss of informationVSLoss of time

Solution Approach 1:

The needle probe performs self-diagnosis by measuring electrical properties directly at the tissue site during the procedure. The device provides immediate feedback about tissue composition and pathology without requiring external laboratory analysis, enabling real-time decision-making during surgery or diagnosis.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The measurement is performed preliminarily during the insertion procedure itself, before any sample removal or transport is needed. By obtaining compositional information in-situ during the initial needle insertion, the system eliminates subsequent time-consuming transport and analysis steps.

Inventive Principle:
Principle #10Preliminary action

3Loss of information

If existing techniques are used to detect tissue properties during surgery, then information can be obtained, but ease of operation decreases due to difficulty in referencing information

Engineering Contradiction:
Improvetissue information availabilityVSAvoidsurgeon accessibility to information
Core Design Contradiction:
Loss of informationVSEase of operation

Solution Approach 1:

The system provides immediate feedback about tissue properties directly to the surgeon during the procedure. The electrical measurements are processed and presented in real-time, allowing the surgeon to adjust their approach based on ongoing tissue characterization without needing to reference external reports or wait for laboratory results.

Inventive Principle:
Principle #23Feedback

4Ease of manufacture

If simple electronics are used in the needle probe, then ease of manufacture and device simplicity improve, but measurement precision may be compromised

Engineering Contradiction:
Improveneedle probe manufacturing simplicityVSAvoidelectrical measurement accuracy
Core Design Contradiction:
Ease of manufactureVSMeasurement precision

Solution Approach 1:

The patent achieves high measurement precision with simple electronics by carefully selecting and optimizing electrical measurement parameters such as frequency, amplitude, and measurement timing. The system measures multiple electrical parameters (impedance, capacitance, resistance) at different frequencies to extract detailed tissue composition information using basic circuitry.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables minimally invasive sensing of tissue properties during surgery, allows early detection of food spoilage and product deterioration, and provides reliable monitoring of medical conditions without requiring sample analysis or container opening.

Implementation Method 1

drive an electrical current through the resistive element to apply heating to the resistive element

Methodology Applied
Scientific EffectJoule heating: Joule Heating

Implementation Method 2

measure an electrical response of the resistive element to the heating to determine compositional information about material in contact with the tip region

Methodology Applied
Scientific EffectThermal conduction: Conduction (thermal)

Data Source

PatentUS20250331730A1Needle probe, apparatus for sensing compositional information, medical drain, method of measuring a thermal property, and method of sensing compositional information
Publication Date: 2025.10.30 OXFORD UNIVERSITY INNOVATION LTD
  • US20250331730A1 patent drawing
  • US20250331730A1 patent drawing
  • US20250331730A1 patent drawing

AI summary

The invention relates to sensing compositional information about material by measuring thermal properties of the material. In one arrangement there is provided a needle probe for sensing compositional information. The probe comprises a needle having a tip region. A resistive element is attached to the needle at the tip region. A measurement system is configured to: 1) drive an electrical current through the resistive element to apply heating to the resistive element, and 2) measure an electrical response of the resistive element to the heating. A processing unit analyses the measured electrical response of the resistive element to the heating to determine compositional information about material in contact with the tip region.