Negative Airway Pressure Training for Oropharyngeal Muscle Tone

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Solution Overview

Problem

Current treatments for obstructive sleep apnea, such as continuous positive airway pressure (PAP) and mandibular advancement devices, face challenges in tracking compliance and efficacy, and surgical interventions lack widespread evidence.

Innovation Solution

A system using a mask with a pump to provide negative airway pressure therapy, measuring one-repetition maximum (1RM) to deliver negative airway pressure of about −1 to −25 cm H2O, exercising the oropharynx and increasing muscle tone to decrease upper airway collapsibility.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If continuous positive airway pressure (PAP) is used to treat obstructive sleep apnea, then airway patency is maintained, but compliance tracking and efficacy monitoring become challenging

Engineering Contradiction:
Improveairway patencyVSAvoidcompliance tracking
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The system automatically tracks compliance and efficacy through integrated sensors that monitor mask wear, breathing patterns, and airway pressure without requiring manual user input or complex external monitoring systems

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The system provides real-time feedback to users and clinicians about compliance levels and treatment efficacy through mobile applications and wireless communication, enabling continuous optimization of therapy

Inventive Principle:
Principle #23Feedback

2Ease of operation

If mandibular advancement devices are used as second line therapy, then compliance can be improved, but the ability to track compliance and efficacy remains a challenge

Engineering Contradiction:
ImprovecomplianceVSAvoidcompliance tracking
Core Design Contradiction:
Ease of operationVSDevice complexity

Solution Approach 1:

The system automatically monitors and reports compliance without requiring manual tracking by the user, using integrated sensors to detect device wear and breathing patterns

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The system can accommodate multiple treatment modalities including PAP, oral appliances, and myofunctional training through a single integrated platform that tracks compliance across different device types

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Reliability

If surgical interventions are performed to target anatomical problems, then structural issues may be corrected, but evidence supporting widespread application is lacking

Engineering Contradiction:
Improveanatomical correctionVSAvoidevidence base
Core Design Contradiction:
ReliabilityVSLoss of information

Solution Approach 1:

The system collects and analyzes real-world data on treatment outcomes, compliance, and efficacy to build an evidence base for myofunctional training and negative airway pressure therapy through continuous monitoring and reporting

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The system enables non-invasive myofunctional training and negative airway pressure therapy as preliminary treatments before considering surgical intervention, providing evidence-based alternatives that may avoid or delay surgery

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system effectively exercises the oropharynx, increasing muscle tone and potentially reducing upper airway collapsibility during sleep, although significant reductions in apnea-hypopnea index (AHI) were not observed in the pilot study.

Implementation Method 1

the pump is capable of creating a pressure of about −1 to −25 cm H2O in the chamber

Methodology Applied
Scientific EffectNegative pressure: Pressure Gradient

Data Source

PatentUS12508382B2Myofunctional training with negative airway pressure for obstructive sleep apnea
Publication Date: 2025.12.30 UNIVERSITY OF ROCHESTER
  • US12508382B2 patent drawing
  • US12508382B2 patent drawing
  • US12508382B2 patent drawing

AI summary

The present invention provides a method and apparatus for treating a subject suffering from obstructive sleep apnea (OSA). In one embodiment, the method of the present invention is configured to deliver negative airway pressure to a subject's airway to strengthen the airway muscle tone.