Negative Pressure Aerosol Mitigation Device for Healthcare Isolation

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Solution Overview

Problem

Healthcare providers are at risk of respiratory infections due to aerosolization and droplet transmission of pathogens from patients, especially during pandemics when PPE is scarce and environmental contamination is high.

Innovation Solution

The development of a negative pressure aerosolization mitigation (NPAM) device that creates a contained negative pressure environment around a patient using an inflatable strut system and a transparent barrier, reducing aerosolization and droplet transmission.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If PPE is used to mitigate transmission, then protection of healthcare providers is improved, but PPE availability deteriorates during pandemics when sourcing is difficult

Engineering Contradiction:
Improveprotection effectivenessVSAvoidPPE availability
Core Design Contradiction:
ReliabilityVSQuantity of substance

Solution Approach 1:

The invention extracts the containment function from PPE and relocates it to the patient care environment through negative pressure aerosolization mitigation devices. The NPAM device creates a controlled negative pressure zone around the patient, extracting the pathogen containment function from provider PPE and placing it in the environmental control system instead.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The NPAM device acts as an intermediary between the patient and healthcare providers. Rather than relying solely on provider PPE as the barrier, the device creates an intermediate negative pressure environment that captures and contains aerosols at their source, serving as a mediator that protects providers without requiring them to wear extensive PPE.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Reliability

If PPE is worn to prevent transmission, then provider protection is improved, but contamination of surfaces and environments is not prevented

Engineering Contradiction:
Improvetransmission preventionVSAvoidenvironmental contamination
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The NPAM device applies preliminary anti-action by capturing aerosols and droplets at their source before they can disperse into the environment or contaminate surfaces. The negative pressure field actively draws airborne pathogens toward collection points, preventing their spread to surfaces and the broader environment before contamination can occur.

Inventive Principle:
Principle #9Preliminary anti-action

Solution Approach 2:

The device converts the harmful dispersal of aerosols into a beneficial containment process. By using negative pressure to draw aerosols toward collection points, the system transforms the potentially harmful random dispersion of pathogens into a controlled flow toward safe containment, turning the harmful aerosol generation into a manageable flow pattern.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

3Object-affected harmful factors

If negative pressure environment is created to contain patients, then aerosolization mitigation is improved, but device complexity increases

Engineering Contradiction:
Improveaerosolization riskVSAvoidNPAM system complexity
Core Design Contradiction:
Object-affected harmful factorsVSDevice complexity

Solution Approach 1:

The NPAM system is segmented into modular functional components: negative pressure generation units, transparent barrier sections, access ports, and sealing mechanisms. This segmentation allows the complex function of aerosol containment to be divided into manageable modules that can be independently configured and maintained.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The transparent barrier of the NPAM device uses flexible thin film materials that can be easily sealed and configured around patients. These flexible barriers simplify the overall structure compared to rigid containment chambers, allowing the complex negative pressure function to be achieved with simpler, more adaptable materials.

Inventive Principle:
Principle #30Flexible shells and thin films

4Illumination intensity

If transparent barrier is used to enclose patient, then visibility for care is improved, but sealing effectiveness may deteriorate

Engineering Contradiction:
ImprovevisibilityVSAvoidsealing effectiveness
Core Design Contradiction:
Illumination intensityVSReliability

Solution Approach 1:

The transparent barrier system uses composite construction combining transparent materials with integrated sealing layers and rigid frame structures. This composite approach maintains optical clarity for visibility while incorporating multiple functional layers that ensure effective sealing at the interfaces between the transparent barrier and the patient environment.

Inventive Principle:
Principle #40Composite materials

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The NPAM device effectively reduces the risk of aerosolization and droplet transmission, providing a safer environment for healthcare providers by containing pathogens within the negative pressure environment, thus reducing the need for extensive PPE usage and environmental contamination.

Implementation Method 1

a negative pressure channel configured to be coupled to a source of negative pressure, and an access port configured to provide a flow limited passageway through the transparent barrier into the volume around the patient when the inflatable strut system is in an inflated state. The negative pressure can be generated in the volume around the patient in response to the application of the source of negative pressure.

Methodology Applied
Scientific EffectNegative pressure: Pressure Gradient

Data Source

PatentUS12310897B2Negative pressure aerosolization mitigation devices and methods
Publication Date: 2025.05.27 UNIVERSITY OF KANSAS
  • US12310897B2 patent drawing
  • US12310897B2 patent drawing
  • US12310897B2 patent drawing

AI summary

An aerosolization mitigation device is provided. The aerosolization mitigation device can include a negative pressure aerosolization mitigation system. A transparent barrier can form a frame of the system, and a negative pressure can be generated in the internal volume. The device can isolate a patient to allow ambulatory, surgical, and routine care to proceed during periods of higher patient volume or viral transmission. The negative pressure environment mitigates viral transmission to protect healthcare providers and others in the vicinity of the patient from health risks during patient care.