Nested Cortical Electrode Delivery System for Minimally Invasive Brain Mapping

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Solution Overview

Problem

Existing brain mapping and stimulation devices using electrodes are highly invasive and complex, necessitating the development of minimally invasive electrode delivery systems and technologies.

Innovation Solution

The development of an electrode delivery system comprising a proximal elongate shaft with a paddle and an irrigation/suction sleeve, where the paddle and sleeve are in fluidic communication, allowing for flexible or rigid configurations and facilitating the deployment of cortical electrodes with multiple electrode segments that can be nested for optimal brain surface coverage.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Object-affected harmful factors

If traditional brain mapping and stimulation devices are used, then brain mapping and stimulation functions are achieved, but the procedure becomes highly invasive and complex

Engineering Contradiction:
ImproveinvasivenessVSAvoidprocedure complexity
Core Design Contradiction:
Object-affected harmful factorsVSDevice complexity

Solution Approach 1:

The electrode segments are nested within the delivery device, with multiple electrode segments contained within a single delivery catheter. The electrodes are collapsed into a compact configuration during delivery and then expanded at the target site, allowing multiple electrodes to be delivered through a single minimally invasive access point while maintaining the capability for complex brain mapping and stimulation functions

Inventive Principle:
Principle #7Nested doll (Nesting)

Solution Approach 2:

The delivery device utilizes a flexible catheter with a collapsible electrode structure that can be compressed into a small profile for delivery through minimally invasive access, then expanded at the target site to provide the necessary electrode surface area for brain mapping and stimulation, thereby reducing invasiveness without sacrificing functional capability

Inventive Principle:
Principle #30Flexible shells and thin films

2Measurement precision

If multiple electrode segments are deployed to improve brain surface coverage, then signal gathering resolution is improved, but device complexity and procedural difficulty increase

Engineering Contradiction:
Improvesignal gathering resolutionVSAvoidelectrode deployment complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

Multiple electrode segments are nested within a single delivery device, allowing them to be delivered together through one access point. The segments can be independently deployed and positioned on the brain surface, providing high signal gathering resolution across multiple locations while simplifying the delivery procedure through a unified delivery mechanism

Inventive Principle:
Principle #7Nested doll (Nesting)

Solution Approach 2:

The electrode array is divided into multiple separate electrode segments that can be independently positioned and deployed. Each segment contains multiple electrode contacts that can be independently activated, allowing for high-resolution signal gathering across different regions of the brain surface while maintaining manageable device complexity through modular design

Inventive Principle:
Principle #1Segmentation

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system enables minimally invasive implantation and effective deployment of cortical electrodes, improving the resolution of signal gathering and reducing the complexity of brain mapping and stimulation procedures.

Implementation Method 1

The irrigation/suction sleeve comprises a sleeve lumen defined within the sleeve and a plurality of holes defined in the sleeve, wherein each of the plurality of holes is in fluidic communication with the sleeve lumen and an area external to the sleeve lumen

Methodology Applied
Scientific EffectFluid flow:

Data Source

PatentUS11883649B2Minimally invasive electrode and delivery device and related systems and methods
Publication Date: 2024.01.30 NEUROONE MEDICAL TECHNOLOGIES CORP
  • US11883649B2 patent drawing
  • US11883649B2 patent drawing
  • US11883649B2 patent drawing

AI summary

Disclosed herein are a minimally invasive electrode and delivery device, along with various related components, devices, methods, and technologies. The delivery device comprises a proximal elongate shaft, a paddle coupled to a distal end of the proximal shaft, and an irrigation/suction sleeve disposable over the paddle. Disclosed also is a fan-like cortical electrode device comprising at least two electrode segments, wherein each of the at least two electrode segments comprises a thin film pad, a plurality of electrode contacts disposed on the thin film pad, and a proximal connector attached to a proximal end of the thin film pad.