Neural Firing Data Profiling System for Content Extraction

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Solution Overview

Problem

Current methods for analyzing neural firing data are inadequate as they fail to accurately capture the information transmitted by neurons, requiring extensive data and being mathematically complex, which limits their application in behavioral experiments and brain-computer interaction.

Innovation Solution

A computer system that profiles neural firing data using time series data within a defined window, incorporating both firing timepoint and frequency, and employs machine learning to extract content without data loss, allowing for efficient classification and quantification of information.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If traditional methods are used to analyze neural firing data, then the analysis can be performed with simple tools, but the accuracy of capturing neural information is insufficient and大量 data is required

Engineering Contradiction:
Improveaccuracy of capturing neural informationVSAvoidamount of data required
Core Design Contradiction:
Measurement precisionVSQuantity of substance

Solution Approach 1:

The patent transforms the analysis approach by changing parameters from traditional firing frequency-only analysis to include precise timing information. The method uses spike timing decomposition into multiple components (e.g., onset, peak, offset times) and analyzes these temporal parameters separately, allowing accurate neural information capture with reduced data requirements.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent segments the continuous neural firing data into discrete temporal components (spike timing parameters). By dividing the firing pattern into specific measurable time points and intervals, the system can extract meaningful information from each segment, improving overall measurement precision without requiring excessive total data.

Inventive Principle:
Principle #1Segmentation

2Measurement precision

If complex mathematical methods are used to extract neural content, then the accuracy of content extraction improves, but the complexity of the method increases making it difficult for behavioral experimenters to use

Engineering Contradiction:
Improveaccuracy of content extractionVSAvoidcomplexity of analysis method
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent replaces complex mathematical decomposition methods with a simplified temporal parameter measurement approach. Instead of using sophisticated algorithms to analyze neural firing patterns, the system measures specific time points (onset, peak, offset) and intervals directly, making the method accessible to behavioral experimenters while maintaining extraction accuracy.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent changes the analytical parameters from complex mathematical transformations to simple temporal measurements. By focusing on directly observable time parameters (when spikes occur relative to stimuli or events), the system achieves accurate content extraction without requiring complex computational methods.

Inventive Principle:
Principle #35Parameter changes

3Ease of operation

If only firing frequency is used in behavioral experiments, then the experiment design is simple, but abundant information contained in firing timepoint is lost

Engineering Contradiction:
Improvesimplicity of experiment designVSAvoidinformation loss from firing timepoint
Core Design Contradiction:
Ease of operationVSLoss of information

Solution Approach 1:

The patent merges the simplicity of frequency-based analysis with the information richness of timing-based analysis. By combining traditional firing rate measurements with precise spike timing parameter measurements (onset, peak, offset times and intervals), the method maintains experimental simplicity while capturing comprehensive neural information that includes both when and how often neurons fire.

Inventive Principle:
Principle #5Merging (Combining)

Data Source

PatentUS20220164631A1Computer system for profiling neural firing data and extracting content, and method thereof
Publication Date: 2022.05.26 KOREA ADVANCED INST OF SCI & TECH
  • US20220164631A1 patent drawing
  • US20220164631A1 patent drawing
  • US20220164631A1 patent drawing

AI summary

Various example embodiments relate to a computer system for profiling neural firing data and extracting content and a method thereof, and it may be configured to profile the neural firing data based on time series data representing firing timepoint for at least one neural firing within a window defined by a predetermined time length, and extract the content for the neural firing from the neural firing data.