Neural Network Bone Density Estimation from Dual Imaging

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Solution Overview

Problem

Current methods for estimating bone density, such as dual x-ray absorptiometry (DXA) and other radiation-based imaging techniques, face challenges in achieving high accuracy due to limitations in data resolution and the complexity of bone structure analysis.

Innovation Solution

An estimation device utilizing a learned neural network that processes both simple radiation images and DXA scanning images, combining three-dimensional CT images with derived attenuation coefficients to enhance bone density estimation, including bone density per unit area, fracture risk evaluation, and recovery state information.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If simple radiation imaging is used for bone density estimation, then the imaging process is simple and fast, but the estimation accuracy is insufficient

Engineering Contradiction:
Improveimaging speedVSAvoidbone density estimation accuracy
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The patent combines simple radiation images with DXA scanning images as dual input for the neural network. This merging of two different imaging modalities allows the system to maintain the speed advantage of simple imaging while incorporating the quantitative accuracy of DXA imaging, thereby resolving the contradiction between imaging speed and estimation accuracy.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The neural network serves as an intermediary that processes and integrates information from both simple radiation images and DXA scanning images. It learns to extract relevant features from both inputs and combines them to produce accurate bone density estimations, acting as a mediator that translates multiple image types into a unified accurate assessment.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Measurement precision

If DXA scanning imaging is used for bone density estimation, then the estimation accuracy improves, but the imaging complexity increases

Engineering Contradiction:
Improvebone density estimation accuracyVSAvoidimaging system complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The system segments the imaging process into two parts: a simple radiation image for initial assessment and a DXA scanning image for detailed analysis. The neural network processes these segmented inputs separately and then integrates them, allowing the system to achieve high accuracy while maintaining operational simplicity through modular processing.

Inventive Principle:
Principle #1Segmentation

3Ease of manufacture

If neural network learning uses only simple radiation images, then the learning process is simple, but the estimation accuracy is limited

Engineering Contradiction:
Improvelearning process simplicityVSAvoidbone density estimation accuracy
Core Design Contradiction:
Ease of manufactureVSMeasurement precision

Solution Approach 1:

The training dataset is constructed as a composite of multiple data types: simple radiation images, DXA scanning images, and ground truth bone density values. This composite training material enables the neural network to learn from diverse inputs, improving estimation accuracy while the structured learning approach maintains relative simplicity in the learning process.

Inventive Principle:
Principle #40Composite materials

4Measurement precision

If multiple imaging modalities are combined for learning, then the estimation accuracy improves, but the data processing complexity increases

Engineering Contradiction:
Improvebone density estimation accuracyVSAvoiddata processing complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The neural network is designed with multi-functionality to handle both simple radiation images and DXA scanning images through a unified architecture. It performs multiple functions: processing different image types, extracting features from each modality, integrating the information, and producing bone density estimations. This universal design reduces processing complexity by using a single system for multiple tasks.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution enables more accurate bone density estimation and fracture risk assessment by leveraging composite two-dimensional images derived from CT data, improving diagnostic precision and recovery state monitoring.

Implementation Method 1

a learned neural network that derives a result of estimation relating to a bone density of a bone part from a simple radiation image acquired by simply imaging a subject including the bone part or a DXA scanning image acquired by imaging the subject by a DXA method

Methodology Applied
Scientific EffectNeural network learning:

Implementation Method 2

a composite two-dimensional image representing the subject, which is derived by combining a three-dimensional CT image of the subject

Methodology Applied
Scientific EffectX-ray attenuation: Absorption (EM radiation)

Data Source

PatentUS12133752B2Estimation device, estimation method, and estimation program
Publication Date: 2024.11.05 FUJIFILM CORP
  • US12133752B2 patent drawing
  • US12133752B2 patent drawing
  • US12133752B2 patent drawing

AI summary

An estimation device includes at least one processor, in which the processor functions as a learned neural network that derives a result of estimation relating to a bone density of a bone part from a simple radiation image acquired by simply imaging a subject including the bone part or a DXA scanning image acquired by imaging the subject by a DXA method. The learned neural network is learned by using, as teacher data, a composite two-dimensional image representing the subject, which is derived by combining a three-dimensional CT image of the subject, and information relating to the bone density of the subject.