Biofuel Cell Using Neural Stem Cells for Scalable Energy

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Solution Overview

Problem

Current biofuel cells employing microorganisms are limited in their application scope and are not suitable for industrial-scale electrical energy production due to high operational costs and lack of sustainability, with existing devices being restricted to specific uses like implantable energy generation in the human body.

Innovation Solution

A biofuel cell utilizing neural stem cell lines, preferably SH-SY5Y cell lines, as electrocytes, combined with a carbon cloth anode and a gas-permeable cathode made from conductive materials, using a medium with glucose, serum, antibiotics, and pH buffers, which allows for scalable and sustainable energy production with enhanced portability and low operational costs.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If microorganisms are employed in biofuel cells for energy generation, then rapid growth and metabolism-based energy production are achieved, but the devices are limited to specific applications like wastewater treatment and implantable use, reducing versatility

Engineering Contradiction:
Improveenergy production capacityVSAvoidapplication scope
Core Design Contradiction:
ProductivityVSAdaptability or versatility

Solution Approach 1:

The patent changes the biological parameter from microorganisms to neural stem cell lines, which exhibit different metabolic characteristics and growth patterns. This parameter change enables the biofuel cell to transition from niche applications to broader industrial-scale energy production while maintaining high productivity through the stem cells' metabolic activity

Inventive Principle:
Principle #35Parameter changes

2Reliability

If conventional biofuel cells are designed for specific applications, then functional performance is optimized, but operational costs increase and sustainability decreases

Engineering Contradiction:
Improvefunctional performanceVSAvoidoperational cost
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The patent creates a universal biofuel cell design using neural stem cell lines that can be applied across multiple sectors including industrial energy production, portable electronics, and medical devices. This multi-functional approach reduces operational costs by eliminating the need for application-specific optimizations and enables sustainable scaling from laboratory to industrial production

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Object-affected harmful factors

If implantable biofuel cells are designed for human body use, then biocompatibility is achieved, but the devices cannot be connected to external electronic devices, reducing adaptability

Engineering Contradiction:
ImprovebiocompatibilityVSAvoiddevice connectivity
Core Design Contradiction:
Object-affected harmful factorsVSAdaptability or versatility

Solution Approach 1:

The patent creates a dynamic system where neural stem cell lines can function in both implantable and external configurations. The biofuel cell design allows flexibility to be connected to external electronic devices when not implanted, enabling the system to adapt between biocompatible enclosed use and versatile external application scenarios

Inventive Principle:
Principle #15Dynamics

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The biofuel cell achieves efficient and sustainable electrical energy generation with adjustable power capacity, enabling the powering of electronic devices through voltage amplification, while minimizing material costs and environmental impact.

Implementation Method 1

Biofuel cells employing microorganisms such as algae and viruses are developed to generate energy over their metabolisms

Methodology Applied
Scientific EffectMetabolism:

Implementation Method 2

a biofuel cell is presented, which comprises an anode provided with neural stem cell lines

Methodology Applied
Scientific EffectElectrochemical reaction:

Data Source

PatentEP3891828B1Electrical energy production using stem cell lines, and a biofuel cell therefor
Publication Date: 2022.07.06 UESKUEDAR UENIVERSITESI
  • EP3891828B1 patent drawingFigure 1
  • EP3891828B1 patent drawingFigure 2
  • EP3891828B1 patent drawingFigure 3

AI summary

The present invention proposes a biofuel cell (1) comprising an anode (2) provided with neural stem cell lines, which preferably include neuroblastoma cell lines, and more preferably include SH-SY5Y cell line. Carbon cloth is found suitable for being used as a cathode material, and also for growing the neural stem cell lines for being used as an anode material. A medium which includes dissolved glucose as carbon source is found to be suitable for growing the neural stem cell lines, and also for being used as electrolyte. A medium comprising a serum such as FBS, FCS or HS; said medium further comprising antibiotics, L-glutamine, glucose and one or more pH buffers is considered within the above definition. The biofuel cell (1) can be scaled up, and/or connected with an amplifier (4) to increase voltage values.