Neural Stimulation Intensity Control Using Activation Charge Rate
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Solution Overview
Problem
Existing methods for electrical stimulation of sensory nerves cannot effectively control the level of intensity of sensory perception, making it difficult for individuals with paralysis or amputation to distinguish between different sensations without visual cues.
Innovation Solution
A system and method that control the perceived intensity of sensory stimuli using an activation charge rate (ACR), which combines pulse frequency and charge per pulse to approximate the total spike rate evoked in the activated neuronal population, allowing for real-time adjustment based on predefined intensity levels and feedback.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If electrical stimulation parameters (pulse frequency or charge per pulse) are modified to affect perception, then sensory perception can be restored to subjects with paralysis or amputation, but the ability to control the level of intensity of sensory perception remains unknown and unavailable
Solution Approach 1:
The patent applies parameter changes by systematically varying electrical stimulation parameters (pulse frequency, charge per pulse, pulse width) to control the activation charge rate (ACR), which directly determines the perceived intensity level. By changing these parameters, the system enables precise control over the intensity of sensory perception while maintaining reliable sensation restoration.
Solution Approach 2:
The patent implements feedback mechanisms where the system monitors and adjusts stimulation parameters based on subject response and predefined intensity levels. This feedback loop allows the system to maintain accurate intensity control by comparing actual perception with target intensity and making real-time parameter adjustments.
2Measurement precision
If stimulation parameters are varied to control perceived intensity, then subjects can distinguish between different sensations, but the complexity of controlling multiple parameters increases
Solution Approach 1:
The patent merges multiple stimulation parameters (pulse frequency, charge per pulse, pulse width) into a single controlling metric called activation charge rate (ACR). This consolidation simplifies the control system by allowing intensity control through one primary parameter rather than independently managing multiple parameters, while still achieving precise intensity discrimination.
Solution Approach 2:
The ACR parameter serves multiple functions: it controls perceived intensity, enables sensation discrimination, and simplifies parameter management. This universal parameter approach allows a single metric to handle what would otherwise require multiple separate control mechanisms, reducing system complexity while maintaining precision.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables individuals to perceive a desired level of sensory intensity by systematically varying the ACR, effectively distinguishing between different sensations and adapting to changes in perception over time.
Implementation Method 1
Sensation can be restored to these subjects through electrical stimulation of sensory nerves, where electrical signals can be transmitted to the brain so that the subject can perceive the sensation without communication from the receptors
Data Source
AI summary
One aspect of the present disclosure relates to a method for controlling levels of perceived intensity of a sensory stimulus. The method includes configuring a stimulation signal with an activation charge rate (ACR) based on a predefined level of intensity by a subject during an action. The ACR is based on a strength of pulses in the stimulation signal parameter and a frequency of pulses in the stimulation signal parameter. The stimulation signal can be applied to neural tissue of a subject during the action. Based on the stimulation signal, the subject can be induced to perceive the predefined level of intensity during the action.