Neuromodulation System Fast Slow Sub-Perception Therapy

The patent segments the neuromodulation therapy into two distinct types: fast-acting sub-perception neuromodulation and slow-acting sub-perception neuromodulation. Each type has different stimulation parameters (fast-acting uses higher frequency 500-5000 Hz with shorter pulse width 20-100 μs, while slow-acting uses lower frequency 10-100 Hz with longer pulse width 100-500 μs). This segmentation allows the system to deliver both types simultaneously or alternately, enabling rapid evaluation of therapeutic effectiveness through the fast-acting component while the slow-acting component provides sustained long-term benefits.

The patent employs parameter changes by adjusting stimulation frequency and pulse width to create two distinct neuromodulation profiles. The fast-acting therapy uses high frequency (500-5000 Hz) and short pulse width (20-100 μs) to achieve rapid pain relief, while the slow-acting therapy uses low frequency (10-100 Hz) and long pulse width (100-500 μs) to provide broader, more position-tolerant coverage. By delivering both types simultaneously or alternately, the system compensates for the fast-acting therapy's sensitivity to lead positioning with the more robust slow-acting therapy, maintaining effective pain relief even if lead positioning is not perfectly precise.

The patent applies preliminary action by delivering fast-acting sub-perception neuromodulation first (or simultaneously with slow-acting therapy) to achieve rapid pain relief within minutes to hours. This fast-acting component acts as a preliminary measure that provides immediate therapeutic benefit while the slow-acting component continues to build its sustained effect over days to weeks. The fast-acting therapy serves as an initial effective intervention that bridges the gap during the prolonged wash-in period of the slow-acting therapy, ensuring continuous pain management without the long delay that would otherwise be experienced.