Cognitive and Neuromotor Assessment System with Dynamic Difficulty

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Solution Overview

Problem

Current systems for assessing neuromotor and neurocognitive disorders, such as Alzheimer's and Parkinson's disease, lack the ability to objectively quantify cognitive and motor functions, failing to provide qualitative measurements and adapt test difficulty based on user performance, and do not correlate test results with patient information like medications or Deep Brain Stimulation parameters.

Innovation Solution

A computer-based system that computes scores for cognitive and neuromotor functions using performance metrics, records user position data, and adjusts test difficulty dynamically, allowing for the aggregation of data to generate composite scores that can be used to classify movement disorders and assess the severity of conditions like Parkinson's disease.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Speed

If computerized systems measure only reaction time to stimulus, then response speed can be quantified, but quality of user interaction cannot be measured

Engineering Contradiction:
Improvereaction timeVSAvoidquality of interaction
Core Design Contradiction:
SpeedVSMeasurement precision

Solution Approach 1:

The system segments the measurement of user interaction into multiple independent components: reaction time measurement, movement quality assessment, accuracy evaluation, and temporal pattern analysis. Each component is measured separately using dedicated sensors and algorithms, allowing comprehensive characterization of cognitive and motor functions without compromising the precision of individual measurements

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system transitions from one-dimensional reaction time measurement to multi-dimensional assessment by adding spatial coordinates, temporal sequences, and quality metrics. The input device tracks not only when the user responds but also the precise trajectory, speed, acceleration, and smoothness of movements, creating a comprehensive performance profile across multiple dimensions

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Ease of operation

If test difficulty is fixed, then test administration is simple, but the system cannot adapt to individual user performance levels

Engineering Contradiction:
Improvetest administrationVSAvoidtest difficulty adaptation
Core Design Contradiction:
Ease of operationVSAdaptability or versatility

Solution Approach 1:

The system implements dynamic test difficulty adjustment by continuously monitoring user performance metrics and automatically modifying subsequent test parameters. When users demonstrate higher competence, the system increases task complexity, speed requirements, or precision demands, ensuring optimal challenge levels are maintained throughout the assessment without manual intervention

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The system incorporates real-time feedback loops where user performance on each test item immediately influences the configuration of subsequent items. The computerized analysis of performance data feeds back into the test administration algorithm, which adjusts difficulty parameters dynamically, creating an adaptive testing experience that responds to individual user capabilities

Inventive Principle:
Principle #23Feedback

3Loss of time

If only overall completion time is measured, then test scoring is simple, but qualitative performance characteristics are lost

Engineering Contradiction:
Improvetest completion timeVSAvoidperformance quality data
Core Design Contradiction:
Loss of timeVSLoss of information

Solution Approach 1:

The system segments the overall completion time into multiple temporal components: reaction time for each stimulus, movement execution time, pause durations, and sequence intervals. This segmentation preserves the total time metric while simultaneously capturing detailed temporal patterns that reveal cognitive processing speed, motor execution efficiency, and attentional characteristics

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system transforms the one-dimensional completion time metric into multi-dimensional performance data by adding spatial trajectory information, velocity profiles, acceleration patterns, and quality scores. This dimensional expansion preserves temporal efficiency measurements while simultaneously capturing rich descriptive information about movement characteristics and interaction quality

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

4Device complexity

If test results are reported without correlation to patient information, then data processing is simple, but clinical interpretation is limited

Engineering Contradiction:
Improvedata processingVSAvoidclinical context
Core Design Contradiction:
Device complexityVSLoss of information

Solution Approach 1:

The system merges performance test data with patient demographic information, medical history, medication profiles, and treatment parameters into a unified dataset. This integration allows the computerized analysis to correlate test performance with clinical variables, generating comprehensive reports that link objective measurements to individual patient contexts for more accurate diagnosis and treatment monitoring

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The system creates a multi-functional data processing framework that simultaneously performs test administration, performance analysis, clinical correlation, and report generation. The same computational platform handles diverse data types including temporal measurements, spatial trajectories, quality metrics, and patient information, enabling comprehensive clinical assessment without proportionally increasing operational complexity

Inventive Principle:
Principle #6Universality (Multi-functionality)

Data Source

PatentUS10741287B2System and method for motor and cognitive analysis
Publication Date: 2020.08.11 THE CLEVELAND CLINIC FOUND
  • US10741287B2 patent drawing
  • US10741287B2 patent drawing
  • US10741287B2 patent drawing

AI summary

In an example embodiment, this disclosure provides a non-transitive computer-readable medium on which are stored instructions executable by a processor, the instructions which, when executed by the processor, cause the processor to perform a method. The method includes computing, based on test performance data of a user, at least one of a performance variable characterizing cognitive functioning and a performance variable characterizing neuromotor functioning. For each of the at least one performance variable, a respective score can be computed based on the respective performance variable and based on a set of performance metrics. The method can also include outputting, via an output device, the at least one computed score.