Neuroprotective Composition for Concussion Recovery

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Solution Overview

Problem

Current treatments for traumatic brain injuries, such as concussions, are inadequate in effectively reducing symptom duration and severity, and there is a need for improved therapeutic options that address the complex pathophysiological processes involved.

Innovation Solution

A composition comprising a combination of natural products including phosphatidylserine, phosphatidylcholine, quercetin, astaxanthin, R-alpha lipoic acid, N-acetyl cysteine, taurine, L-glutamine, carnitine, D-ribose, creatine, epigallocatechin gallate, melatonin, ginkgo leaf extract, curcumin, and L-glycine, which works synergistically to limit inflammation, improve energy production, augment circulation, restore capillary integrity, and promote tissue repair.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of manufacture

If traditional physical and cognitive rest is used to treat concussions, then the treatment is simple and non-invasive, but the symptom duration and severity are not effectively reduced

Engineering Contradiction:
Improvetreatment simplicityVSAvoidrecovery speed
Core Design Contradiction:
Ease of manufactureVSProductivity

Solution Approach 1:

The patent applies the composite materials principle by combining multiple natural product ingredients (such as phosphatidylserine, phosphatidylcholine, quercetin, astaxanthin, and other antioxidants) into a composite nutritional formulation. This composite approach creates a synergistic effect that accelerates concussion recovery more effectively than traditional single-method treatments like rest alone, while maintaining ease of administration through oral supplementation.

Inventive Principle:
Principle #40Composite materials

2Device complexity

If no active treatment is provided for traumatic brain injury, then the treatment approach is simple, but the duration and severity of symptoms remain prolonged

Engineering Contradiction:
Improvetreatment complexityVSAvoidsymptom duration
Core Design Contradiction:
Device complexityVSLoss of time

Solution Approach 1:

The patent applies preliminary action by providing a nutritional formulation designed to be administered during the acute phase of concussion recovery, before prolonged symptoms can set in. The composition includes ingredients that proactively support neuroprotection, reduce inflammation, and accelerate cellular repair processes, thereby preventing the establishment of chronic post-concussive symptoms rather than merely treating them after they develop.

Inventive Principle:
Principle #10Preliminary action

3Reliability

If a combination of multiple natural products is used to treat concussion, then the therapeutic effectiveness is improved, but the composition complexity increases

Engineering Contradiction:
Improvetreatment effectivenessVSAvoidcomposition complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent applies universality by designing a multi-functional nutritional formulation where each ingredient serves multiple purposes in concussion recovery. For example, antioxidants like astaxanthin and quercetin simultaneously provide neuroprotection, reduce inflammation, and support cellular energy production. This multi-functionality allows the composition to address multiple pathophysiological aspects of concussion with a single supplement regimen, managing complexity while maintaining high effectiveness.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Data Source

PatentUS9101580B2Compositions and methods for treating traumatic brain injury
Publication Date: 2015.08.11 HAVN LIFE SCI INC
  • US9101580B2 patent drawing
  • US9101580B2 patent drawing
  • US9101580B2 patent drawing

AI summary

The disclosure provides compositions treating traumatic brain injuries such as concussions. In one embodiment, the composition comprises phosphatidylserine, phosphatidylcholine, quercetin, astaxanthin, R-alpha lipoic acid, N-acetyl cysteine, taurine, L-glutamine, carnitine, D-ribose, creatine, epigallocatechin gallate, melatonin, ginkgo leaf extract, curcumin and L-glycine. The disclosure also provides methods for treating traumatic brain injuries such as concussions by administering an effective amount of the compositions described within.