Nasal High Flow Therapy Flow Setting via Peak Inspiratory Flow

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Current methods for setting flow rates in nasal high flow therapy systems often result in inappropriate flow rates, either too high or too low, leading to inadequate oxygen delivery or increased patient breathing work, due to the need for trial and error and lack of precision in determining the optimal setting based on patient-specific inspiratory demands.

Innovation Solution

Determining the flow setting for nasal high flow therapy by measuring the peak inspiratory flow during a spontaneous breathing mode in mechanical ventilation, allowing for precise adjustment to deliver the desired fraction of inspired oxygen (FiO2) while minimizing backpressure and patient discomfort.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If trial and error method is used to determine flow setting, then the system can eventually achieve desired FiO2, but the time required and patient discomfort increase

Engineering Contradiction:
Improveflow setting accuracyVSAvoidtime to achieve desired FiO2
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent applies preliminary action by measuring the patient's peak inspiratory flow during mechanical ventilation before transitioning to NHF therapy. This pre-measurement allows the NHF flow setting to be determined in advance based on actual patient demand data, eliminating the need for trial-and-error adjustments after therapy initiation.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent uses feedback by utilizing the peak inspiratory flow measurement from mechanical ventilation as input data to automatically determine the appropriate NHF flow setting. This feedback loop ensures the flow setting is based on actual patient respiratory demand rather than estimation or trial and error.

Inventive Principle:
Principle #23Feedback

2Reliability

If high flow setting is used to ensure adequate oxygen delivery, then FiO2 requirement is met, but patient breathing work and discomfort increase

Engineering Contradiction:
Improveoxygen delivery adequacyVSAvoidpatient breathing work
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent applies parameter changes by setting the NHF flow rate based on the measured peak inspiratory flow parameter from mechanical ventilation. This dynamic parameter adjustment ensures the flow is high enough to meet oxygen delivery requirements but not excessively high to cause increased breathing work or discomfort.

Inventive Principle:
Principle #35Parameter changes

3Object-affected harmful factors

If low flow setting is used to minimize patient discomfort, then breathing work is reduced, but adequate FiO2 delivery cannot be ensured

Engineering Contradiction:
Improvepatient breathing workVSAvoidoxygen delivery adequacy
Core Design Contradiction:
Object-affected harmful factorsVSReliability

Solution Approach 1:

The patent uses parameter changes to set the NHF flow rate equal to or slightly above the measured peak inspiratory flow. This ensures the flow is low enough to minimize breathing work but high enough to prevent room air entrainment and ensure adequate FiO2 delivery, as the flow matches actual patient demand.

Inventive Principle:
Principle #35Parameter changes

4Ease of operation

If standard-based flow setting is used for NHF therapy, then initial setup is simplified, but precision in meeting patient-specific demands is reduced

Engineering Contradiction:
Improveflow setting setupVSAvoidpatient-specific flow accuracy
Core Design Contradiction:
Ease of operationVSMeasurement precision

Solution Approach 1:

The patent applies self-service by having the system automatically determine the NHF flow setting using the peak inspiratory flow data already collected during mechanical ventilation. This eliminates the need for clinicians to manually estimate or calculate appropriate flow settings based on patient characteristics, providing both ease of operation and patient-specific precision.

Inventive Principle:
Principle #25Self-service

Data Source

PatentUS11298484B2Method and systems for executing nasal high flow therapy with settings determined from flow outputs during a previous ventilation mode
Publication Date: 2022.04.12 GE PRECISION HEALTHCARE LLC
  • US11298484B2 patent drawing
  • US11298484B2 patent drawing
  • US11298484B2 patent drawing

AI summary

Various methods and systems are provided for performing nasal high flow therapy. In one example, a method for respiratory support includes: delivering an air and oxygen mixture for nasal high flow therapy to a patient at a flow setting, the flow setting determined based on a peak inspiratory flow obtained during a previous, spontaneous breathing mode during mechanical ventilation of the patient. The flow setting may be a flow rate of a heated and humidified mixture of air and oxygen delivered via a high flow nasal cannula.