Nickel-Chromium-Iron Biosensor Electrode via PVD

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Solution Overview

Problem

Current biosensors using non-noble metal electrodes face challenges in achieving consistent and accurate glucose measurements due to deviations in electrochemical responses and inadequate electron transfer kinetics, making them unsuitable replacements for noble metal electrodes, while also being cost-prohibitive.

Innovation Solution

A biosensor electrode comprising a substrate with a conductive layer made of a nickel-chromium alloy, with specific weight percent ranges of nickel and chromium, and optionally including iron, manganese, copper, and silicon, coated via physical vapor deposition, which provides improved electrochemical properties and reduced manufacturing costs.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of manufacture

If non-noble metal electrodes are used to reduce manufacturing costs, then cost is reduced, but electrochemical response consistency and measurement accuracy deteriorate

Engineering Contradiction:
Improvemanufacturing costVSAvoidglucose measurement accuracy
Core Design Contradiction:
Ease of manufactureVSMeasurement precision

Solution Approach 1:

The patent changes the compositional parameters of the electrode material from pure noble metals to non-noble metal alloys with specific compositions. By carefully controlling the alloy composition (e.g., nickel-chromium-iron with specific weight percentages), the electrode achieves both cost reduction and maintained measurement accuracy through optimized material parameters.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent employs composite alloy materials combining multiple non-noble metals (nickel, chromium, iron, and trace elements) to create an electrode that replicates the electrochemical properties of noble metals. This composite approach allows cost reduction while maintaining or improving electrochemical response consistency through synergistic material combinations.

Inventive Principle:
Principle #40Composite materials

2Ease of manufacture

If non-noble metal electrodes are used to reduce manufacturing costs, then cost is reduced, but electron transfer kinetics deteriorate

Engineering Contradiction:
Improvemanufacturing costVSAvoidelectron transfer kinetics
Core Design Contradiction:
Ease of manufactureVSReliability

Solution Approach 1:

The patent optimizes the compositional parameters of the non-noble metal alloy to enhance electron transfer kinetics. By adjusting the ratios of nickel, chromium, iron, and trace elements, the electrode achieves reliable electron transfer rates comparable to noble metals, resolving the kinetics deficiency while maintaining cost advantages.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent introduces trace elements (manganese, copper, silicon) at specific concentrations to locally enhance electron transfer properties at the electrode surface. These localized compositional adjustments improve electron transfer kinetics without significantly increasing overall manufacturing cost.

Inventive Principle:
Principle #3Local quality

3Ease of manufacture

If non-noble metal electrodes are used to reduce manufacturing costs, then cost is reduced, but anodic stability deteriorates

Engineering Contradiction:
Improvemanufacturing costVSAvoidanodic stability
Core Design Contradiction:
Ease of manufactureVSStability of the object's composition

Solution Approach 1:

The patent uses composite alloy materials where chromium and iron components provide corrosion resistance and anodic stability. The synergistic combination of nickel-chromium-iron with trace elements creates a stable electrochemical interface that resists oxidation and maintains composition stability, matching noble metal performance at lower cost.

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The patent controls the compositional parameters, particularly chromium and iron content, to enhance anodic stability. By optimizing these parameters within specific ranges, the electrode achieves improved resistance to anodic dissolution and oxidation, ensuring long-term stability without requiring expensive noble metals.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The nickel-chromium alloy electrodes offer consistent and accurate glucose measurements with enhanced electron transfer kinetics and anodic stability, reducing manufacturing costs and improving the reliability of biosensors.

Implementation Method 1

coated via physical vapor deposition

Methodology Applied
Scientific EffectPhysical vapor deposition: Physical Vapour Deposition

Data Source

PatentUS11835481B2Physical vapor deposited biosensor components
Publication Date: 2023.12.05 EASTMAN CHEM CO
  • US11835481B2 patent drawing
  • US11835481B2 patent drawing
  • US11835481B2 patent drawing

AI summary

A biosensor component is provided that provides enhanced characteristics for use in biosensors, such as blood glucose sensors. The biosensor component comprises a substrate and a conductive layer coated on the substrate. The conductive layer includes nickel, chromium, and iron, such that a combined weight percent of the nickel and chromium in the conductive layer is in the range of 80 to less than 95 weight percent, and the weight percent of iron in the conductive layer is greater than 5 weight percent and less than 12 weight percent.