Nicotinamide Mononucleotide Visual Function Improvement
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Solution Overview
Problem
The increasing burden on eyes from prolonged use of electronic devices, combined with poor lifestyle habits, leads to vision loss and related health issues such as eye fatigue, blurred vision, and VDT syndrome, for which existing solutions like glasses and dietary supplements are either burdensome or lack proven effectiveness.
Innovation Solution
A visual function improving agent containing nicotinamide mononucleotide as an active ingredient, which promotes NAD+ biosynthesis and activates sirtuin-dependent deacetylases, thereby improving eye strain, blurred vision, and VDT syndrome symptoms, and can be formulated as a food or medicinal product.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If glasses and contact lenses are used to improve visual function, then visual acuity is improved, but ease of operation deteriorates due to burden of wearing and maintaining them
Solution Approach 1:
The patent replaces the mechanical system of glasses and contact lenses with a biochemical system using nicotinamide mononucleotide supplementation. This eliminates the need for physical devices that require wearing and maintenance, while still achieving visual function improvement through metabolic pathways.
Solution Approach 2:
The patent introduces nicotinamide mononucleotide as an intermediary substance that mediates between diet and visual function. This intermediary approach allows improvement of visual acuity without direct mechanical intervention, instead using biochemical pathways to achieve the desired effect.
2Measurement precision
If recovery training methods are used to improve eyesight, then visual function may be improved, but reliability deteriorates because effects are not sufficiently proved and continuation is difficult
Solution Approach 1:
The patent changes the fundamental parameter from behavioral training to biochemical supplementation. By using nicotinamide mononucleotide to directly supplement NAD+ levels in the body, the approach relies on established metabolic pathways rather than unproven training effects, thereby improving reliability.
Solution Approach 2:
The patent enables the body's visual system to self-repair through nicotinamide mononucleotide supplementation. The substance is converted into NAD+ which then supports the function of sirtuins and other enzymes that naturally maintain and repair ocular tissues, allowing the body to serve itself without requiring continuous external training intervention.
3Reliability
If balanced diet containing vitamins is maintained to improve visual function, then health of visual function is maintained, but ease of operation deteriorates due to difficulty in daily continuation
Solution Approach 1:
The patent extracts the essential active component needed for visual function maintenance from the complex balanced diet. Instead of requiring multiple vitamins and minerals, it focuses on nicotinamide mononucleotide as the key substance that directly supports NAD+ production and visual health, simplifying the intervention to a single supplement.
Solution Approach 2:
The patent leverages the multi-functionality of nicotinamide mononucleotide, which serves multiple roles: it is a precursor for NAD+ synthesis, supports sirtuin activity for cellular repair, and provides antioxidant protection. This single substance addresses multiple aspects of visual health that would otherwise require a complex combination of different vitamins and nutrients.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The agent effectively improves and maintains visual function, preventing and slowing the progression of eye strain, blurred vision, and VDT syndrome symptoms, with safe long-term intake and minimal side effects.
Implementation Method 1
nicotinamide mononucleotide as an active ingredient for use in an improvement of eye strain, of blurred vision, of presbyopia or of a VDT syndrome
Implementation Method 2
promotes NAD+ biosynthesis and activates sirtuin-dependent deacetylases
Implementation Method 3
activates sirtuin-dependent deacetylases, thereby improving eye strain, blurred vision, and VDT syndrome symptoms
Data Source
Figure 1
AI summary
PROBLEM: To provide an improving agent and an improving method for a visual function that is safe in long-term intake and ensures effective improvement of the visual function. SOLUTION: Nicotinamide mononucleotide is contained as an active ingredient.