Stable Nicotine Gel Composition for Leak-Free Storage

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Solution Overview

Problem

Existing nicotine compositions, particularly in gel form, are not stable and prone to releasing or absorbing a liquid phase, leading to potential leakage and instability over a range of environmental conditions.

Innovation Solution

A composition comprising a gelling agent in the range of 2% to 7% by weight, including biopolymers like xanthan gum and low acyl gellan, glycerol, levulinic acid, and calcium ions, which forms a stable gel phase that maintains shape and mass under varying humidity conditions.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Object-affected harmful factors

If gel forms of nicotine compositions are used, then leakage concerns are reduced, but the compositions are not physically stable and may release liquid phase

Engineering Contradiction:
ImproveleakageVSAvoidphysical stability
Core Design Contradiction:
Object-affected harmful factorsVSStability of the object's composition

Solution Approach 1:

The patent applies parameter changes by carefully controlling the concentration ranges of key components: water (10-30% w/w), glycerol (65-85% w/w), and nicotine (0.5-5% w/w). These specific parameter ranges transform the composition from an unstable gel that releases liquid phase to a stable formulation that maintains its gel structure under various storage conditions, thereby resolving the contradiction between reduced leakage and physical stability.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent uses a composite material system combining water, glycerol, and nicotine in specific proportions. This composite formulation creates a synergistic effect where the components work together to maintain gel stability, preventing both liquid phase separation and leakage while ensuring physical stability across different storage conditions.

Inventive Principle:
Principle #40Composite materials

2Object-affected harmful factors

If gel forms of nicotine compositions are used, then leakage concerns are reduced, but the compositions are not stable over a broad range of storage conditions

Engineering Contradiction:
ImproveleakageVSAvoidstability over storage conditions
Core Design Contradiction:
Object-affected harmful factorsVSAdaptability or versatility

Solution Approach 1:

The patent optimizes the composition parameters to achieve stability across a broad range of storage conditions. By adjusting the water content to 10-30% w/w and glycerol to 65-85% w/w, the formulation maintains its gel structure and prevents leakage whether stored at refrigerated temperatures or ambient conditions, demonstrating adaptability to various storage environments.

Inventive Principle:
Principle #35Parameter changes

3Object-affected harmful factors

If gel forms of nicotine compositions are used, then leakage concerns are reduced, but the compositions release or absorb liquid phase

Engineering Contradiction:
ImproveleakageVSAvoidliquid phase release
Core Design Contradiction:
Object-affected harmful factorsVSLoss of substance

Solution Approach 1:

The patent controls the liquid phase release by precisely adjusting the composition parameters, particularly the water-glycerol ratio. By maintaining water at 10-30% w/w and glycerol at 65-85% w/w, the formulation achieves a balanced state where the gel structure remains intact and prevents both release and absorption of liquid phase, eliminating the harmful effect while maintaining leakage protection.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The stable gel composition retains its shape and mass without releasing or absorbing water, ensuring predictable form and stability from manufacture to consumption, suitable for use in aerosol-generating devices.

Implementation Method 1

a gelling agent in a range from about 2% to about 7% by weight, the gelling agent forming a solid medium

Methodology Applied
Scientific EffectGel formation: Gel

Implementation Method 2

The stable gel composition retains its shape and mass without releasing or absorbing water

Methodology Applied
Scientific EffectHygroscopic equilibrium: Absorption (physical)

Data Source

PatentEP3772254B1Nicotine gel
Publication Date: 2025.11.05 PHILIP MORRIS PRODUCTS SA
  • EP3772254B1 patent drawing
  • EP3772254B1 patent drawing
  • EP3772254B1 patent drawing

AI summary

A composition includes a gelling agent forming a solid medium, glycerol dispersed in the solid medium, and nicotine dispersed in the glycerol. The composition is a stable gel phase.