Nicotine Oral Delivery Pouch with Chewing Gum for Rapid Sustained Release
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Solution Overview
Problem
Current nicotine delivery products, such as snus, dissolvable tobacco, and nicotine chewing gums, fail to provide a rapid initial absorption of nicotine followed by sustained release, limiting user control over nicotine intake and not replicating the smoking experience effectively.
Innovation Solution
A nicotine oral delivery product featuring a powder enclosed in a water-insoluble pouch that is permeable to saliva, allowing for initial rapid and sustained nicotine release, achieved by combining nicotine with a chewing gum composition that transforms into a coherent mass upon chewing, enabling user-controlled nicotine boost.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Duration of action of moving object
If nicotine is released slowly from snus or NRT products, then sustained nicotine levels are achieved, but rapid initial nicotine absorption is not provided
Solution Approach 1:
The nicotine delivery system is segmented into two distinct components: a rapid-release portion (snus or dissolvable tobacco) and a sustained-release portion (chewing gum with nicotine). This segmentation allows each component to fulfill its specific function - the rapid-release portion provides immediate nicotine absorption while the chewing gum portion provides sustained release over time.
Solution Approach 2:
The rapid-release nicotine portion is consumed first to establish immediate nicotine levels, followed by the chewing gum portion that continues nicotine delivery. This preliminary action of rapid delivery precedes the sustained release phase, mimicking the smoking experience's initial rapid absorption followed by sustained effects.
2Duration of action of moving object
If nicotine products are designed for passive nicotine release, then sustained absorption is achieved, but user control over nicotine release rate is limited
Solution Approach 1:
The chewing gum portion is designed to be dynamically controllable by the user. The user can chew the gum at varying intensities and frequencies to modulate the nicotine release rate according to their immediate needs, providing dynamic control over the delivery system while maintaining sustained release capability.
Solution Approach 2:
The system incorporates user feedback through the chewing action. The user monitors their nicotine levels and cravings, then adjusts their chewing behavior accordingly - chewing more intensively or frequently when additional nicotine is needed, and reducing chewing when satisfied, creating a feedback-controlled nicotine delivery system.
3Speed
If chewing tobacco is used to achieve rapid nicotine release, then initial nicotine satisfaction is provided, but excessive saliva production occurs
Solution Approach 1:
The harmful effect of excessive saliva production is extracted and separated from the beneficial effect of rapid nicotine release. The rapid-release nicotine portion is designed to dissolve or disintegrate without requiring extensive chewing, thereby achieving rapid nicotine delivery without the excessive saliva production that characterizes traditional chewing tobacco.
Solution Approach 2:
The rapid-release nicotine portion is designed as a single-use, short-lived component that dissolves or disintegrates quickly in the mouth, providing rapid nicotine delivery and then being discarded. This disposable approach eliminates the need for prolonged chewing that would generate excessive saliva.
4Duration of action of moving object
If nicotine chewing gum is chewed to achieve nicotine release, then sustained nicotine delivery is achieved, but rapid initial nicotine peak is not provided
Solution Approach 1:
Two different nicotine delivery mechanisms are merged into a single product system: a rapid-release nicotine component (snus or dissolvable tobacco) and a sustained-release nicotine component (chewing gum). The rapid-release portion provides the initial nicotine peak while the chewing gum portion provides sustained delivery, combining the advantages of both approaches.
Solution Approach 2:
The rapid-release nicotine portion is consumed first as a preliminary action to establish immediate nicotine levels and peak concentration. Following this preliminary rapid delivery, the chewing gum portion is then used to maintain sustained nicotine levels, creating a two-phase delivery pattern that mimics smoking.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The product provides a rapid and sustained nicotine release, mimicking the smoking experience, allowing users to control nicotine intake, thereby aiding in smoking cessation or reduction with improved user satisfaction.
Implementation Method 1
pouch is permeable for saliva and therein dissolved parts of the powder
Implementation Method 2
chewing gum composition that transforms into a coherent mass upon chewing
Data Source
AI summary
A nicotine oral delivery product contains a powder enclosed in a water insoluble pouch, wherein the pouch is permeable for saliva and therein dissolved parts of the powder, wherein the powder comprises at least (a) nicotine selected from the group consisting of tobacco, nicotine salts, nicotine base, stabilized nicotine, and mixtures thereof corresponding to 0.1 to 20 mg nicotine in the form of nicotine base and (b) a chewing gum composition. A method is provided for producing the nicotine oral delivery product.