Nineteen-Lens Broadband Objective for High-Resolution Large-Field Imaging
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Solution Overview
Problem
Existing microscope objective lenses face challenges in achieving a large field of view and high resolution, particularly in biological imaging, especially when using two-photon imaging, and have limited working wavebands that do not cover visible light and near-infrared ranges.
Innovation Solution
A large-field of view, high-resolution broadband objective lens comprising nineteen spherical lenses arranged on the same optical axis, with specific configurations and parameters to enhance imaging capabilities, including cemented lenses and optimized refractive indices, allowing for a wide field of view and high numerical aperture.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If the numerical aperture of the objective lens is increased to improve resolution, then the resolution is improved, but the field of view decreases
Solution Approach 1:
The objective lens is divided into 19 individual spherical lens elements arranged in sequence along the optical axis. These lenses are grouped into multiple cemented lens units (e.g., first and second lenses form a cemented lens, third, fourth and fifth lenses form another cemented lens). This segmentation allows each lens element to contribute to different aspects of optical performance, enabling simultaneous achievement of high numerical aperture (0.5-1.0) and large field of view (≥6mm) by distributing the optical correction functions across multiple elements.
2Adaptability or versatility
If the working waveband is expanded to cover visible light and near-infrared bands, then the adaptability is improved, but the manufacturing precision requirement increases
Solution Approach 1:
The objective lens employs multiple lens elements made from different optical materials with varying refractive indices and dispersion characteristics. Specific lenses use materials such as BK7, SF5, F2, LAF1, and other optical glass types. This composite material approach enables the lens to achieve broadband performance across visible (400-700nm) and near-infrared (700-1000nm) wavelengths by compensating for chromatic aberrations through the combined optical properties of different materials, while maintaining feasible manufacturing precision requirements.
3Reliability
If a cemented lens structure is used to reduce the number of air gaps, then the imaging quality is improved, but the manufacturing complexity increases
Solution Approach 1:
The objective lens incorporates multiple cemented lens units where adjacent lens elements are optically bonded together without air gaps. Specifically, the first and second lenses form a cemented lens, the third, fourth and fifth lenses form another cemented lens, and similar combinations continue through the 19-lens structure. This merging eliminates air-glass interfaces that would cause reflections and scattering, thereby improving imaging quality and reducing ghost images. The cemented structure is achieved through optical adhesive bonding, which, while requiring precise alignment during manufacturing, provides a reliable and repeatable process that balances manufacturing complexity with performance benefits.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The lens achieves a super-large effective field of view with high numerical aperture, improving imaging throughput and enabling high-resolution imaging of large-scale samples across visible light and near-infrared bands, suitable for multispectral excited single-photon and two-photon fluorescence imaging.
Implementation Method 1
a large-field of view, high-resolution broadband objective lens comprising nineteen spherical lenses arranged on the same optical axis
Data Source
AI summary
A large-field of view, high-resolution broadband objective lens, which comprises nineteen spherical lenses that are arranged on the same optical axis. The nineteen lenses sequentially comprise, from an object side to an image side: a first lens, a second lens, a third lens, a fourth lens, a fifth lens, a sixth lens, a seventh lens, an eighth lens, a ninth lens, a tenth lens, an eleventh lens, a twelfth lens, a thirteenth lens, a fourteenth lens, a fifteenth lens, a sixteenth lens, a seventeenth lens, an eighteenth lens and a nineteenth lens. Compared with previous similar objective lenses, the objective lens has a higher resolution, a larger imaging field of view and a wider working waveband, and can meet the requirement for visible light and near-infrared two-photon, large-field of view, high-resolution imaging.


