Nitrate-Salt Amino Acid Compositions for Rapid Vasodilation
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Conventional amino acids, nitrates, and nitrites lack properties such as rapid vasodilation, effective bioabsorption, and solubility, limiting their effectiveness in dietary supplements for athletic performance and health benefits.
Innovation Solution
Development of amino acid compositions comprising Carnitine, Taurine, and Nitrate compounds or compositions, including derivatives like acetyl-L-Carnitine and propionyl-L-carnitine, which are synthesized by combining amino acids with nitric or nitrous acid to form nitrate or nitrite salts, enhancing vasodilative characteristics and bioavailability.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional amino acids, nitrates, and nitrites are used alone, then the composition is simple, but the vasodilative characteristics and bioabsorption are insufficient
Solution Approach 1:
The patent combines amino acids (carnitine, taurine) with nitrate compounds into a single compositional formulation, merging the vasodilative properties of nitrates with the metabolic benefits of amino acids to achieve enhanced therapeutic effect while maintaining a relatively simple two-component structure
Solution Approach 2:
The invention creates a composite material system where amino acids and nitrate compounds work synergistically, producing a composition that exhibits properties superior to the individual components, specifically enhanced vasodilative characteristics and bioabsorption
2Reliability
If conventional amino acids and nitrates are used separately, then the manufacturing process is simple, but the solubility and bioabsorption are limited
Solution Approach 1:
The patent merges amino acids and nitrate compounds into a unified compositional formulation that improves solubility and bioabsorption characteristics, allowing the body to more effectively absorb and utilize the vasodilative components while maintaining straightforward manufacturing procedures
3Speed
If conventional nitrates are used alone, then the dosage can be high, but the rapid vasodilation effect is not achieved
Solution Approach 1:
The patent changes the chemical and physiological parameters by combining nitrate compounds with specific amino acids, which modifies the release kinetics and bioavailability of the nitrate, enabling faster vasodilation at lower dosage levels through enhanced metabolic processing
Data Source
AI summary
Methods of improving pharmacodynamic properties of an amino acid in a human subject is disclosed. The method comprises administering to the human subject the amino acid in the form of a nitrate salt, wherein the nitrate salt form of the amino acid is faster acting compared to other forms of the amino acid.