Nitrone Herbicide Compounds Selective Weed Control

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Solution Overview

Problem

Current herbicides for controlling undesirable vegetation in crops like rice, soybean, and sugar beet are not effective enough, costly, toxic, or environmentally unsafe, and lack diverse modes of action.

Innovation Solution

Development of nitrone compounds, their N-oxides, and salts, which are used in herbicidal compositions that include surfactants and other active ingredients to selectively control weeds by contacting the vegetation or its environment, providing a more effective and environmentally safer option.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If current herbicides are used to control undesirable vegetation, then weed control is achieved, but efficacy is insufficient and costs increase

Engineering Contradiction:
Improveweed control efficacyVSAvoidcrop efficiency
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

The patent applies parameter changes by modifying the chemical structure of herbicide compounds to create nitrone compounds with improved biological activity. The specific chemical parameters (molecular structure, functional groups) are changed to enhance weed control efficacy while maintaining selectivity for different crop types.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent employs composite materials by formulating nitrone compounds with surfactants and other adjuvants to create enhanced herbicidal compositions. These composite formulations improve the overall efficacy, stability, and performance of the herbicide beyond what the active compound alone could achieve.

Inventive Principle:
Principle #40Composite materials

2Reliability

If current herbicides are used for weed control, then vegetation is controlled, but environmental safety is compromised

Engineering Contradiction:
Improveweed control effectivenessVSAvoidenvironmental safety
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent converts potentially harmful substances into beneficial ones by designing nitrone compounds that selectively target weed biological processes while sparing crop plants. The chemical structure is engineered to exploit differences in metabolism or physiology between weeds and crops, turning what could be non-selective toxicity into selective herbicidal action.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

Solution Approach 2:

The patent applies local quality by creating herbicides with site-specific activity tailored to particular weed species or growth stages. The nitrone compounds are designed to interact with specific biological targets in weeds while having minimal impact on crops, achieving localized effectiveness without broad environmental harm.

Inventive Principle:
Principle #3Local quality

3Reliability

If current herbicides are applied, then weed growth is controlled, but toxicity increases

Engineering Contradiction:
Improveherbicidal activityVSAvoidtoxicity
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The patent uses parameter changes by optimizing the chemical parameters of herbicide molecules to achieve maximum herbicidal activity at minimal toxic doses. The molecular weight, solubility, and reactivity parameters are adjusted to enhance potency, allowing lower application rates that reduce overall toxicity while maintaining effective weed control.

Inventive Principle:
Principle #35Parameter changes

4Reliability

If conventional herbicides are used, then vegetation control is achieved, but mode of action diversity is limited

Engineering Contradiction:
Improveweed controlVSAvoidsite of action diversity
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent applies segmentation by developing a series of nitrone compound variants, each targeting different biological pathways or sites of action in weeds. Instead of relying on a single mode of action, the patent segments the herbicidal activity into multiple mechanisms (e.g., photosynthesis inhibition, enzyme disruption, membrane damage) to provide versatility against different weed species and reduce resistance development.

Inventive Principle:
Principle #1Segmentation

Data Source

PatentEP3558962B1Nitrone herbicides
Publication Date: 2023.07.12 FMC CORP
  • EP3558962B1 patent drawing
  • EP3558962B1 patent drawing
  • EP3558962B1 patent drawing

AI summary

Disclosed are compounds of Formula 1, including all stereoisomers, N-oxides, and salts thereof, wherein R1, R2, R3, R4, R5, R6, J2, Q1, Q2, T and Y are as defined in the disclosure. Also disclosed are compositions containing the compounds, N-oxides and salts, and methods for controlling undesired vegetation comprising contacting the undesired vegetation or its environment with an effective amount of a compound, N-oxide, salt or composition.