N-Vinyl Lactam Polymer Additive for Sustained-Release Chemical Agents

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Chemical agents often exhibit low persistence of effects and poor sensory experiences, such as short-lasting coolness, due to inadequate sustained-release properties.

Innovation Solution

A polymer additive containing 50 mol % to 100 mol % of an N-vinyl lactam-based monomer, with a specific average particle diameter and crosslinked structure, is used to enhance the performance of chemical agents by improving their sustained-release properties and sensory experiences.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Duration of action of moving object

If conventional chemical agents are used, then basic functional effects are achieved, but persistence of effects and sustained-release properties are insufficient

Engineering Contradiction:
Improvepersistence of effectsVSAvoidsustained-release property
Core Design Contradiction:
Duration of action of moving objectVSReliability

Solution Approach 1:

The patent uses a composite gel structure formed by crosslinking N-vinyl lactam-based polymer with dicarboxylic acid or dicarboxylic acid anhydride. This composite material combines the polymer matrix with crosslinking agents to create a network structure that provides both extended duration of action and reliable sustained-release properties through controlled drug diffusion pathways.

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The gel structure created by the crosslinked network forms a porous matrix that allows controlled release of medicinal agents. The porous structure provides channels for drug diffusion while maintaining gel integrity, enabling sustained-release over extended periods without compromising structural stability.

Inventive Principle:
Principle #31Porous materials

2Ease of operation

If chemical agents are applied, then functional effects are produced, but sensory experiences such as coolness sensation are poor

Engineering Contradiction:
Improvesensory experienceVSAvoidsensation persistence
Core Design Contradiction:
Ease of operationVSDuration of action of moving object

Solution Approach 1:

The crosslinked gel composite enhances sensory experience by providing a structured matrix that controls the release profile of sensory-active compounds. The gel network maintains consistent contact with the application surface while releasing active ingredients at controlled rates, improving both immediate sensory perception and prolonged sensation persistence.

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

By adjusting the crosslinking degree, polymer composition, and gel structure parameters, the patent optimizes the release kinetics of sensory-active compounds. This parameter control allows tuning of both the intensity and duration of sensory effects such as coolness sensation, addressing both sensory quality and persistence requirements.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The polymer additive significantly enhances the persistence of effects and sensory experiences of chemical agents, providing a more prolonged and improved sensation of coolness and application feel.

Implementation Method 1

a gelling agent for a sustained-release chemical agent, which is used by absorbing a sustained-release chemical agent

Methodology Applied
Scientific EffectAbsorption: Absorption (physical)

Data Source

PatentUS11964042B2Additive for medicinal agents
Publication Date: 2024.04.23 NIPPON SHOKUBAI CO LTD
  • US11964042B2 patent drawing
  • US11964042B2 patent drawing

AI summary

Provided is an additive for a chemical agent, which is capable of improving the functions of various chemical agents. The additive for a chemical agent according to an embodiment of the present invention includes a polymer (I) containing 50 mol % to 100 mol % of a structural unit derived from an N-vinyl lactam-based monomer with respect to 100 mol % of structural units derived from all monomers, the additive for a chemical agent having an average particle diameter of 100 μm or less in a state of having been dried under a reduced pressure of 0.02 MPa or less at 100° C. for 1 hour.