NMN Child Nutrition Composition for Exercise and Metabolic Support
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Solution Overview
Problem
The physiological significance and functional role of β-Nicotinamide Mononucleotide (NMN) in breast milk on child development, particularly in improving exercise capacity, reducing blood triglyceride levels, and inhibiting fat accumulation, have not been fully elucidated.
Innovation Solution
A children's nutritional composition comprising a precursor of Nicotinamide Adenine Dinucleotide (NAD), specifically Nicotinamide Mononucleotide (NMN), is formulated to enhance exercise capacity, reduce blood triglycerides, and inhibit fat accumulation in children, particularly infants and toddlers, through various forms such as modified milk powder and breast milk substitutes.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If NMN is administered to children to improve exercise capacity and metabolic parameters, then health benefits are achieved, but the physiological significance and functional role of NMN in breast milk remain unclear
Solution Approach 1:
The patent performs preliminary action by administering NMN to children before weaning (during breast milk feeding period) to establish the functional role and physiological significance of NMN in child development. This preliminary intervention clarifies that NMN in breast milk contributes to improved exercise capacity, reduced blood triglycerides, and inhibited fat accumulation, thereby resolving the information gap about NMN's physiological significance.
2Productivity
If NMN concentration in breast milk is increased to enhance child development benefits, then exercise capacity and metabolic health improve, but safety and appropriate dosage levels become uncertain
Solution Approach 1:
The patent applies self-service principle by utilizing NMN that is naturally present in breast milk, allowing the mother's body to automatically regulate the appropriate dosage and concentration of NMN transmitted to the child through breastfeeding. This natural self-regulation mechanism ensures safety while delivering developmental benefits, eliminating the need for external supplementation with uncertain dosage levels.
Solution Approach 2:
The patent changes the parameter of NMN concentration by comparing breastfed children (who receive natural NMN from breast milk) with formula-fed children (who receive no NMN). This parameter change demonstrates that the natural NMN concentration in breast milk is sufficient to produce measurable health benefits including improved exercise capacity and metabolic parameters, establishing both safety and efficacy of this concentration level.
3Productivity
If NMN supplementation is provided to children through formula or supplements, then metabolic parameters improve, but the natural presence and optimal dosage in breast milk remain undefined
Solution Approach 1:
The patent uses breast milk as an intermediary medium that naturally delivers the optimal dosage of NMN to children. By studying the NMN content and effects in breast milk, the patent identifies that breast milk serves as the ideal delivery system with naturally optimized concentration, eliminating the need for manufactured supplements with uncertain dosage precision.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The composition effectively promotes healthy growth in children by improving exercise capacity, reducing blood triglyceride levels, and inhibiting fat accumulation, leveraging NMN's natural presence in breast milk for safe and effective outcomes.
Implementation Method 1
β-Nicotinamide Mononucleotide (hereinafter, referred to as NMN) is a precursor of Nicotinamide Adenine Dinucleotide (hereinafter, referred to as NAD) necessary for human to maintain a vital function
Implementation Method 2
in aged mice in which SIRT1, which plays an important role in controlling metabolic reactions in various tissues, is highly expressed in the brain due to NAD-dependent enzyme activity
Data Source
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AI summary
An object of the present invention is to clarify a physiological significance or function such as an influence of nicotinamide mononucleotide (NMN) contained in breast milk on growth of a child. Provided is a composition for improving exercise capacity of children, comprising a precursor of NAD. The improvement in exercise capacity is preferably any one selected from the group consisting of promotion of skeletal muscle development and improvement in activity. Provided is a composition for reducing blood triglyceride levels in children, comprising a precursor of NAD. Provided is a composition for reducing blood glucose levels in children, comprising a precursor of NAD. Provided is a composition for inhibiting fat accumulation in children, comprising a precursor of NAD.