Nodule Feature Extraction Using Vessel Tree Context

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Solution Overview

Problem

Current automatic nodule detection techniques in chest x-ray images struggle to differentiate genuine nodules from false positives due to the lack of effective feature extraction methods that incorporate contextual background information, particularly in handling complex background structures and weak nodules.

Innovation Solution

The method extracts nodule features by utilizing contextual background information, specifically vessel tree structures, to differentiate false positives from genuine nodules by calculating features based on the relationship between nodules and underlying vessel tree contexts, employing a pseudo-segmentation and propagation algorithm to define background information and derive quantitative representations.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If conventional feature extraction techniques (adaptive ring filtering, matching filtering) are used, then some nodule detection capability is achieved, but the ability to differentiate genuine nodules from false positives in complex backgrounds is insufficient

Engineering Contradiction:
Improvenodule detection accuracyVSAvoidfalse positive rate
Core Design Contradiction:
Measurement precisionVSReliability

Solution Approach 1:

The patent segments the feature extraction process into multiple components: local nodule characteristics (shape, intensity, texture) and global background contextual information (vessel tree structures, anatomical patterns). This segmentation allows independent optimization of each feature type and their subsequent combination, improving the ability to distinguish genuine nodules from false positives by considering both local and global contexts

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent introduces background contextual information as an intermediary element that mediates between the nodule candidate and the classification decision. By incorporating vessel tree structures and anatomical background patterns, the system gains additional discriminatory power to resolve ambiguities between genuine nodules and false positives that cannot be resolved by local nodule features alone

Inventive Principle:
Principle #24Intermediary (Mediator)

2Device complexity

If simple features are extracted at candidate positions, then the feature extraction process is simple, but the features lack sufficient discriminating capability to separate genuine nodules from false positives

Engineering Contradiction:
Improvefeature extraction complexityVSAvoidfeature discrimination capability
Core Design Contradiction:
Device complexityVSMeasurement precision

Solution Approach 1:

The patent merges two types of features: simple local nodule features (easier to compute) and background contextual features (more computationally intensive but provide superior discrimination). This combination allows the system to maintain computational efficiency from simple features while gaining the enhanced discrimination capability from complex background analysis, resolving the trade-off between complexity and precision

Inventive Principle:
Principle #5Merging (Combining)

Data Source

PatentUS8224057B2Method and system for nodule feature extraction using background contextual information in chest x-ray images
Publication Date: 2012.07.17 SIEMENS HEALTHINEERS AG
  • US8224057B2 patent drawing
  • US8224057B2 patent drawing
  • US8224057B2 patent drawing

AI summary

A method and system for nodule feature extract using background contextual information in chest x-ray images is disclosed. In order to detect false positives in nodule candidates for a chest x-ray image, background contextual information, such as contextual vessel tree information, is defined in the chest x-ray image. Features are extracted for each nodule candidate based on the background contextual information, and the extracted features are used to detect whether each nodule candidate is a false positive or a genuine nodule.