Nomogram-Based Sphere Correction for Laser Vision Refractive Errors

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Solution Overview

Problem

Current laser vision correction systems, such as the Zyoptix® system, often result in overcorrection of refractive errors due to the use of preprogrammed instructions that do not account for individual variations in higher-order aberrations, leading to suboptimal postoperative outcomes, with a significant percentage of patients requiring re-treatment and experiencing residual refractive errors.

Innovation Solution

A nomogram-based system that calculates the amount of sphere correction using preoperative manifest refraction and higher-order aberrations data, specifically accounting for interactions between lower- and higher-order aberrations to refine the laser ablation process, reducing spherical overcorrection and improving postoperative refractive outcomes.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If preprogrammed instructions are used for laser ablation, then the surgical process is simplified and faster, but manufacturing precision deteriorates due to overcorrection of refractive errors

Engineering Contradiction:
Improvesurgical process efficiencyVSAvoidrefractive error correction accuracy
Core Design Contradiction:
ProductivityVSManufacturing precision

Solution Approach 1:

The patent modifies the preprogrammed instruction parameters by introducing nomogram-based calculations that adjust the amount of sphere correction based on preoperative manifest refraction and higher-order aberrations data. This changes the ablation parameters dynamically rather than using fixed preprogrammed values, resolving the contradiction by maintaining surgical efficiency while improving correction accuracy through personalized parameter adjustment

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent performs preliminary calculations using nomograms before the actual laser ablation to determine the precise amount of sphere correction needed. This preliminary action accounts for individual variations in higher-order aberrations and their interactions with lower-order aberrations, allowing the surgical process to proceed efficiently with pre-calculated accurate parameters that prevent overcorrection

Inventive Principle:
Principle #10Preliminary action

2Device complexity

If preprogrammed instructions are used for laser ablation, then device complexity is reduced, but measurement precision deteriorates in predicting postoperative refractive error

Engineering Contradiction:
Improvesystem programming complexityVSAvoidpostoperative refractive error prediction accuracy
Core Design Contradiction:
Device complexityVSMeasurement precision

Solution Approach 1:

The patent introduces nomograms as an intermediary computational tool between the preprogrammed instruction system and the actual laser ablation process. These nomograms serve as a mediator that translates preoperative data (manifest refraction and higher-order aberrations) into corrected ablation parameters, thereby improving prediction accuracy without significantly increasing the complexity of the laser system itself

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent replaces the mechanical reliance on fixed preprogrammed instructions with a computational approach using nomogram-based calculations. This substitution introduces mathematical models that account for higher-order aberration interactions, improving measurement precision while keeping the physical laser system relatively simple

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Ease of operation

If individual variations in higher-order aberrations are not accounted for, then ease of operation is maintained, but reliability deteriorates with significant percentage of patients requiring re-treatment

Engineering Contradiction:
Improvesurgical procedure simplicityVSAvoidpostoperative outcome consistency
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The patent performs preliminary nomogram-based calculations before surgery to account for individual variations in higher-order aberrations. This preliminary action ensures that each patient's unique optical characteristics are considered in advance, improving reliability by preventing overcorrection while maintaining ease of operation during the actual surgical procedure

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent incorporates feedback mechanisms by using preoperative manifest refraction and higher-order aberrations data to adjust the ablation plan. This feedback loop allows the system to learn from individual patient characteristics and optimize treatment parameters accordingly, improving reliability without significantly complicating the surgical workflow

Inventive Principle:
Principle #23Feedback

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The proposed system achieves a higher percentage of patients with uncorrected visual acuity of 20/20 or better, minimizing the need for re-treatment and reducing the range of postoperative refractive errors to within ±1 diopter, thereby enhancing the precision and effectiveness of customized LASIK procedures.

Implementation Method 1

a programmed series of ablating laser pulses are directed onto a patient's eye to reshape the cornea

Methodology Applied
Scientific EffectLaser ablation: Laser Ablation

Data Source

PatentUS8273077B2System and method for treating vision refractive errors
Publication Date: 2012.09.25 UNIVERSITY OF ROCHESTER
  • US8273077B2 patent drawing
  • US8273077B2 patent drawing
  • US8273077B2 patent drawing

AI summary

Disclosed is a computer-implemented method for correcting refractive errors in a living eye using a laser vision correction system that involves first calculating an amount of sphere based on preoperative manifest refraction and higher order aberrations data associated with the eye, and then correcting for the calculated amount of sphere by ablating at least a portion of the eye. The preoperative manifest refraction may include preoperative manifest sphere, preoperative spherical equivalent, regular astigmatism, and oblique astigmatism, and the preoperative higher-order aberrations may include 4th-order spherical and 3rd root mean square. Other factors may also be used to adjust the calculated amount of sphere. A device readable medium for storing the calculation and instructions for operating a laser vision correction system for practicing the method is also disclosed, as is a method of treating refractive errors.