Non-invasive Analysis Through Hole Light Intensity
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Solution Overview
Problem
The existing non-invasive analysis system struggles with accurately analyzing biological components due to the rapid diffusion of absorption heat throughout the optical medium, resulting in a small change in the traveling direction of the probe light.
Innovation Solution
A non-invasive substance analysis apparatus is designed with a sample support plate featuring a through hole that allows excitation light to directly reach the sample, increasing light intensity and absorption heat, while minimizing heat escape through the use of a low-thermal-conductivity material.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Illumination intensity
If excitation light is applied to the sample through the sample support plate, then the light intensity reaching the sample is reduced due to absorption by the plate, but providing a through hole increases light intensity and absorption heat
Solution Approach 1:
The sample support plate is segmented by introducing a through hole, dividing the plate structure into regions with and without material. This allows excitation light to pass through the hole directly to the sample without being absorbed by the plate material, thereby increasing light intensity while maintaining structural integrity of the surrounding plate areas.
Solution Approach 2:
The problematic material (sample support plate) is extracted or removed from the light path by creating a through hole. This eliminates the absorption of excitation light by the plate material, allowing maximum light intensity to reach the sample and generate sufficient absorption heat for accurate temperature detection.
2Measurement precision
If the sample support plate uses material with high thermal conductivity, then heat dissipates quickly making temperature detection difficult, but using low thermal conductivity material reduces heat escape and enhances temperature signal
Solution Approach 1:
The sample support plate is designed with spatially varying thermal conductivity properties. The region around the through hole where the sample is placed uses low thermal conductivity material to trap heat locally and enhance the temperature signal for detection. Other regions of the plate may have different thermal properties to maintain structural stability and prevent excessive heat accumulation.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This configuration enhances the accuracy of substance analysis by increasing the absorption heat and reducing heat loss, resulting in a more significant temperature signal and improved analysis precision.
Implementation Method 1
The excitation light source emits excitation light toward a sample placed on the sample placement region. The excitation light is applied to the sample through the through hole.
Implementation Method 2
The infrared light is absorbed by the biological sample, which causes the biological sample to generate heat. A degree of absorption heat of the biological sample depends on an amount or concentration of a biological component in the sample or on a surface of the sample.
Implementation Method 3
The temperature sensor is provided on the first main surface. The absorption heat of the sample becomes less likely to escape in a thickness direction of the sample support plate. A temperature signal output from the temperature sensor during irradiation of the sample with the excitation light increases.
Data Source
AI summary
A non-invasive substance analysis apparatus includes: a sample support plate; an excitation light source; and a temperature sensor. The sample support plate has a main surface including a sample placement region, and a main surface opposite to the main surface. The temperature sensor is provided on the main surface. A through hole extending from the sample placement region to the main surface is provided in the sample support plate. Excitation light emitted from the excitation light source is applied to a sample placed on the sample placement region through the through hole.