Non-Planar Optics Module for Analyte Detection
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Solution Overview
Problem
Existing analyte detection systems in offset testing devices face challenges such as limited speed, high equipment costs, reduced ruggedness, and difficulty in obtaining valid test results, especially in non-laboratory settings.
Innovation Solution
The system employs a non-planar optics module with an angled upper tier platform and a lower tier platform, an incubator, an imaging device, and a direct, dynamically-controlled lighting assembly to enhance analyte detection efficiency and accuracy.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If traditional optical systems are used in offset testing devices, then the device structure is simple, but the measurement precision and detection accuracy are limited
Solution Approach 1:
The patent introduces a non-planar optical path that extends in three-dimensional space, using angled light paths and multi-level optical components. This transforms the traditional two-dimensional optical layout into a three-dimensional configuration, allowing improved measurement precision while managing device footprint and component arrangement.
Solution Approach 2:
The optical system employs nested arrangements where optical components are positioned within compact housings, and multiple optical elements are arranged in concentric or layered configurations. This nesting approach allows complex optical functionality to be achieved within a constrained physical envelope.
2Reliability
If traditional planar optical platforms are used, then the device is easy to manufacture, but the ruggedness and resistance to vibration are reduced
Solution Approach 1:
The optical system is divided into modular segments or assemblies, each containing specific optical components mounted on independent platforms or holders. This segmentation allows each module to be manufactured and tested separately, then assembled into the complete system, improving both ruggedness through modular reinforcement and ease of manufacture through standardized production of individual modules.
Solution Approach 2:
The patent employs curved or angled optical platforms and non-planar mounting surfaces instead of flat rigid mounts. These curved geometries provide mechanical compliance that absorbs vibrations and thermal expansion, enhancing ruggedness while the modular nature of the curved components maintains manufacturability.
3Productivity
If conventional optical paths are used, then the device complexity is low, but the speed and efficiency of analyte detection are limited
Solution Approach 1:
The optical system is designed to maintain continuous illumination and detection during the entire assay process. The non-planar optical path allows light to continuously traverse the sample area without mechanical interruption, enabling real-time monitoring and faster detection kinetics compared to systems requiring mechanical scanning or intermittent measurement.
Solution Approach 2:
The optical system performs preliminary alignment and focus adjustments during device assembly or initialization, establishing optimal detection conditions before the actual assay begins. This preliminary configuration eliminates the need for time-consuming adjustments during testing, thereby increasing productivity.
4Reliability
If standard optical alignment methods are used, then the ease of operation is good, but the ability to prevent fraudulent use of pre-run assays is insufficient
Solution Approach 1:
The optical system incorporates feedback mechanisms that monitor alignment status, light intensity, and detection signals in real-time. These feedback signals are used to verify that the assay is being performed under correct conditions and to detect attempts to use pre-run or fraudulent assays, maintaining reliability while requiring minimal user intervention through automated verification.
Solution Approach 2:
The optical system employs dynamic alignment features that automatically adjust component positions during operation to maintain optimal detection geometry. This dynamic adaptation ensures valid results regardless of minor variations in assay placement, preventing fraudulent use while maintaining ease of operation through automated correction rather than manual adjustment.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This configuration improves the speed, ruggedness, and ease of use of analyte detection, while ensuring the validity of test results and preventing fraudulent use of pre-run assays.
Implementation Method 1
The sample is carried to the opposite end of the membrane strip by a mobile phase that traverses the membrane strip, for example by capillary action.
Implementation Method 2
The presence and, in some cases, the concentration, of an analyte on a reagent strip may be determined by measuring the optical reflectance from an area of development on the strip.
Data Source
AI summary
Analyte testing devices, assemblies, methods, operations, and systems are shown and described. In one embodiment, an apparatus to generate a test result from an assay, when contacted with a sample, includes a non-planar optics module, an imaging device, and a direct, dynamically-controlled lighting assembly. The assembly may include an aperture carrier heat block having a plurality of optical windows and enhancing manipulation of an assay about the assembly.