Nonionic Melt-Blown Fiber Web for Wound Care
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Current wound care materials, such as alginate and carboxymethyl cellulose, deactivate cationic antiseptics, and rayon binds antimicrobial molecules, limiting their effectiveness in wound dressings.
Innovation Solution
Development of non-ionic melt-blown nonwoven fiber webs using a copolymer of divalent hydroxyethylene and dihydroxybutylene monomer units, allowing for the creation of a fiber web that avoids deactivation of cationic antiseptics and is non-toxic to human cells, by combining primary fibers with secondary fibers to form a multi-component fiber web.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Quantity of substance
If alginate or carboxymethyl cellulose is used as wound care material, then high hydrophilicity and absorbency are achieved, but cationic antiseptics are deactivated
Solution Approach 1:
The patent changes the chemical parameter of the fiber material from anionic (alginate, carboxymethyl cellulose) to non-ionic (polyvinyl alcohol copolymer). This parameter change maintains the hydrophilic and absorbent properties while eliminating the deactivation of cationic antiseptics, thus resolving the contradiction between absorbency and antiseptic efficacy.
Solution Approach 2:
The patent uses a composite fiber structure consisting of a polyvinyl alcohol copolymer backbone with pendant hydroxyl groups. This composite structure combines the hydrophilic properties needed for absorbency with the non-ionic character that preserves antiseptic activity, simultaneously achieving both requirements.
2Quantity of substance
If rayon is used as wound care material, then high hydrophilicity is achieved, but cationic antimicrobial molecules are bound
Solution Approach 1:
The patent changes the charge parameter of the material from anionic (rayon) to non-ionic (polyvinyl alcohol copolymer). This eliminates the binding interaction with cationic antimicrobial molecules while preserving hydrophilicity through the copolymer's molecular structure, thus maintaining antimicrobial effectiveness.
3Ease of manufacture
If conventional melt-blown nonwoven fiber webs are used, then manufacturing simplicity is maintained, but deactivation of cationic antiseptics occurs
Solution Approach 1:
The patent modifies the polymer composition parameter by using a polyvinyl alcohol copolymer with specific copolymerization ratios (5-50 mol% of the second monomer). This compositional change allows the material to be manufactured using conventional melt-blown processes while eliminating the anionic character that causes antiseptic deactivation.
Data Source
AI summary
A method of making a nonwoven fiber web comprises: providing a melt-blown nonwoven fiber web comprising bonded primary fibers having an average fiber diameter of 2 to 100 microns, wherein the primary fibers comprise a copolymer comprising divalent hydroxyethylene monomer units and divalent dihydroxybutylene monomer units; opening at least a portion of the melt-blown nonwoven fiber web to provide loose primary fibers; combining the loose primary fibers with secondary fibers; and forming a secondary nonwoven fiber web comprising the primary fibers and secondary fibers. A fiber web preparable according to the method and a multicomponent fiber including a first phase comprising a copolymer comprising divalent hydroxyethylene monomer units and divalent dihydroxybutylene monomer units and a second phase comprising a non-biodegradable polymer.