Novel Protein Regulating Proteolytic Activity and Cell Invasiveness

The patent introduces a novel protein as an intermediary substance that mediates regulation between multiple physiological processes (proteolytic activity, cell invasiveness, smooth muscle contraction). This single protein acts as a multifunctional regulator that coordinates these previously unrelated processes, thereby achieving broad therapeutic effects across different disease types including perinatal diseases, cancer, and inflammatory diseases.

Instead of searching for regulatory proteins within known motif structures, the patent inverts the approach by identifying a protein with no known motif structure that possesses regulatory functions. This inversion led to the discovery of a completely novel protein family with unique structural characteristics that enable regulatory actions on proteolytic activity, cell invasiveness, and smooth muscle contraction that were previously unrecognized.

The patent describes a protein that performs multiple functions simultaneously: it exhibits proteolytic activity itself while also regulating the activity of other proteases, controls cell invasiveness, and modulates smooth muscle contraction. This multi-functionality allows a single protein to address multiple pathological processes involved in disease development and progression.