Biochemical Analysis Nozzle Height Comparison for Bubble Error Detection

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Solution Overview

Problem

Biochemical analysis apparatuses fail to recognize errors when the nozzle detects an air bubble or other issues above the liquid surface, leading to incorrect suction processes and potential analysis failures.

Innovation Solution

Incorporating a controller that stores and compares the heights of nozzle detection with the accommodation object, providing distinct error notifications based on the difference in heights to identify and address errors such as air bubbles or other obstructions.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If the sensor detects contact of the nozzle with the accommodation object to trigger suction, then the suction process can be initiated, but false detection of air bubbles as liquid surface causes erroneous suction attempts

Engineering Contradiction:
Improvedetection accuracyVSAvoiderror detection mechanism
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The system uses feedback by comparing the current nozzle height at detection with the previous nozzle height stored in memory. This feedback mechanism allows the system to recognize abnormal patterns (such as air bubbles causing false high detections) and trigger appropriate error notifications, thereby improving detection reliability without requiring complex additional hardware

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The system performs preliminary action by storing the nozzle height information in advance before the actual suction operation. This preliminary recording of height data enables the system to perform comparative analysis and detect errors before erroneous suction occurs, preventing waste of reagents and improving overall process reliability

Inventive Principle:
Principle #10Preliminary action

2Loss of information

If the nozzle height is not monitored and compared, then the system remains simple, but errors such as air bubbles cannot be recognized and notified to the user

Engineering Contradiction:
Improveerror informationVSAvoidheight storage and comparison system
Core Design Contradiction:
Loss of informationVSDevice complexity

Solution Approach 1:

The system implements feedback by continuously monitoring nozzle height and comparing it with previously stored values. When an anomaly is detected (such as the nozzle detecting an air bubble at an unexpectedly high position), the system generates error information and notifies the user, thereby preventing loss of critical error information while maintaining relatively simple system architecture

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The memory device acts as an intermediary that stores nozzle height information for later comparison. This intermediary storage mechanism enables the system to retain and compare height data without requiring complex real-time processing, thus preventing information loss while minimizing the increase in device complexity

Inventive Principle:
Principle #24Intermediary (Mediator)

Data Source

PatentUS12145155B2Biochemical analysis apparatus and biochemical analysis method
Publication Date: 2024.11.19 SHIMADZU CORP
  • US12145155B2 patent drawing
  • US12145155B2 patent drawing
  • US12145155B2 patent drawing

AI summary

A controller detects an error based on a most recent height of a nozzle at detection of contact of a nozzle with a sample by a liquid surface sensor and a previous height of the nozzle at detection of contact of the nozzle with the sample by the liquid surface sensor, and upon detection of the error, provides an error notification in a manner different from that at detection of another error.