Nozzle Device Microjet Segmentation Skin Permeation
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Solution Overview
Problem
Current needle-free syringes face challenges in uniformly delivering liquids into the skin without causing pain or bleeding, especially when dealing with high viscosity fluids, due to variations in skin thickness and properties, leading to inefficient penetration and loss of the injected substance.
Innovation Solution
A minimally invasive injection device featuring a nozzle with a micro-scale outlet and injection part, detachably connected to a reservoir, which generates a microjet and is designed to penetrate the skin to a preset depth, utilizing adjustable pressure and multiple injection points to ensure uniform delivery and minimize discomfort and loss.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Object-affected harmful factors
If a needle-free syringe is used to eject liquid as high pressure microjet, then pain and bleeding are minimized, but uniform permeation into skin becomes difficult due to skin variations
Solution Approach 1:
The invention divides the single microjet into multiple microjets by providing multiple outlets (at least two) in the nozzle. This segmentation allows the liquid to be delivered through multiple points simultaneously, compensating for skin variations and achieving more uniform permeation while maintaining the painless, needle-free advantage.
Solution Approach 2:
The invention applies different characteristics to different parts of the nozzle system. The outlets are arranged at specific intervals and orientations, with each outlet potentially having different injection parameters (pressure, flow rate, angle) to adapt to local skin variations at different injection sites, thereby achieving uniform overall permeation.
2Speed
If high pressure is applied to generate sufficient microjet velocity, then skin permeation capability is improved, but injection loss increases when microjet is not properly diffused
Solution Approach 1:
By dividing the single high-velocity microjet into multiple lower-velocity microjets, the invention reduces the likelihood of microjet collision and backflow. Each microjet can be more effectively diffused into the skin without the harmful interference of subsequent microjets, thereby reducing injection loss while maintaining adequate permeation capability.
Solution Approach 2:
The invention uses multiple outlets to deliver a distributed amount of liquid rather than concentrating all liquid in a single high-velocity jet. This partial action approach ensures that even if some microjets have insufficient velocity, the cumulative effect achieves the required permeation while reducing loss from failed injections.
3Manufacturing precision
If multiple outlets are provided to compensate for skin variations, then uniform delivery is improved, but device complexity increases
Solution Approach 1:
The nozzle structure with multiple outlets serves multiple functions simultaneously: it compensates for skin variations, reduces microjet collision, and provides uniform delivery. This multi-functionality justifies the increased complexity by achieving multiple benefits from a single structural modification.
Solution Approach 2:
The invention changes the geometric parameters of the nozzle (number of outlets, outlet spacing, outlet orientation) to optimize performance. By carefully selecting these parameters, the device achieves uniform delivery without requiring overly complex control systems or additional components.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The device effectively minimizes pain and bleeding while ensuring uniform delivery of liquids to the desired depth, independent of skin characteristics and fluid properties, reducing injection loss and enhancing permeation efficiency.
Implementation Method 1
a pressure providing part including a first pressure applying part connected to the first reservoir part and configured to apply pressure to the liquid, and a first pressure generator to provide the pressure to the first pressure applying part
Implementation Method 2
an outlet to generate a microjet of the liquid
Data Source
AI summary
Disclosed is a nozzle device and a minimally invasive injection device, and the nozzle device for a minimally invasive injection device according to an exemplary embodiment includes an outlet to generate a microjet of a liquid, and an injection part of a micro-scale size connected to the outlet and adapted to be inserted into a skin tissue to a preset depth.